676273-39-5Relevant articles and documents
H-bonding vs Protonation of Alkynes in Regioselective Hydroamination Reactions: A Glimpse into the Reactivity of Arylogous Ynolethers and Ynamines
Abe, Masahiro,Jean, Alexandre,Blanchet, Jér?me,Rouden, Jacques,Maddaluno, Jacques,De Paolis, Micha?l
, p. 15448 - 15475 (2019/11/29)
In this paper is described the competition and transition between hydrogen bonding and protonation of alkynes connected, on one side, to various aromatic rings and to chiral amino ester appendages on the other side. While the first mode of activation indu
Synthesis of a serotonin reuptake inhibitor
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Page/Page column, (2014/09/29)
Process for the preparation of the piperazinyl derivative vilazodone, having activity as a serotonin reuptake inhibitor and used in therapy for treating serious symptoms of depression in adults, and its synthetic intermediates.
AZOLE COMPOUNDS AS PIM INHIBITORS
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, (2012/10/08)
The invention relates to bicyclic compounds of formulas I and Ia, and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of Pim-1 and/or Pim-2, and/or Pim-3 protein kinase activity or enzyme function. In still further em