109216-61-7

Basic information

• Product Name: 2H-Indazole-3-carboxylic acid,2-methyl-, methyl ester
• Synonyms: 2H-Indazole-3-carboxylic acid,2-methyl-, methyl ester;methyl 2-methylindazole-3-carboxylate
• CAS NO: 109216-61-7
• Molecular Formula: C10H10N2O2
• Molecular Weight: 190.2
• Mol File: 109216-61-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2H-Indazole-3-carboxylic acid,2-methyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Indazole-3-carboxylic acid,2-methyl-, methyl ester(109216-61-7)
• EPA Substance Registry System: 2H-Indazole-3-carboxylic acid,2-methyl-, methyl ester(109216-61-7)

Safety Data

• Hazardous Substances Data: 109216-61-7(Hazardous Substances Data)

Usage

General Description

2H-Indazole-3-carboxylic acid, 2-methyl-, methyl ester is a chemical compound with the molecular formula C11H11N3O2. It is a methyl ester derivative of 2H-indazole-3-carboxylic acid, a heterocyclic organic compound. This chemical is used in the synthesis of various pharmaceuticals and agrochemicals. It can also be used as a building block for the preparation of various organic compounds and intermediates. Additionally, this compound has potential applications in the field of medicinal chemistry and drug discovery due to its pharmacological properties and biological activities.

Upstream product

• 43120-28-1 methyl 1H-indazole-3-carboxylate 
• 74-88-4 methyl iodide 
• 4498-67-3 1H-Indazole-3-carboxylic acid 
• 4838-00-0 2-methyl-2H-indazole 
• 79-22-1 methyl chloroformate 
• 77-78-1 dimethyl sulfate 
• 186581-53-3 diazomethane 

Downstream Products

• 181071-92-1 2-methyl-2H-indazole-3-carbonyl chloride 
• 34252-44-3 2-Methylindazole-3-carboxylic acid 

Relevant articles and documents

Efficient syntheses of exo-granisetron hydrochloride and other potential impurities present in granisetron hydrochloride, an anti-emetic drug

European Pharmacopeia mentions about nine potential impurities in Granisetron hydrochloride. These impurities need to be controlled in the API as described in the Pharmacopeia. Elegant syntheses of four potential impurities in Granisetron hydrochloride are disclosed.

Convenient method for the 3-functionalization of isoindazoles

The C-3 position of isoindazoles is readily functionalized by metalation with lithium diisopropylamide followed by reaction with a variety of electrophiles. Copyright Taylor & Francis LLC.

Indazoles as indole bioisosteres: Synthesis and evaluation of the tropanyl ester and amide of indazole-3-carboxylate as antagonists at the serotonin 5HT3 receptor

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