34252-44-3 Usage
Description
2-METHYL-2H-INDAZOLE-3-CARBOXYLIC ACID is an organic compound characterized by its white solid appearance. It is a key component in the synthesis of various ligands, particularly those targeting 5-HT2A and 5-HT3 receptors. These ligands play a significant role in the treatment of central nervous system (CNS)-related disorders.
Uses
Used in Pharmaceutical Industry:
2-METHYL-2H-INDAZOLE-3-CARBOXYLIC ACID is used as a reagent for the synthesis of 5-HT2A and 5-HT3 receptor ligands. These ligands are crucial in the development of medications aimed at treating a range of CNS-related disorders. 2-METHYL-2H-INDAZOLE-3-CARBOXYLIC ACID's involvement in the creation of these ligands highlights its importance in the pharmaceutical industry, as it contributes to the advancement of treatments for various neurological conditions.
Used in Research and Development:
In addition to its application in the pharmaceutical industry, 2-METHYL-2H-INDAZOLE-3-CARBOXYLIC ACID is also utilized in research and development. Scientists and researchers employ this compound to study the interactions between 5-HT2A and 5-HT3 receptors and their respective ligands. This knowledge is vital for understanding the underlying mechanisms of CNS-related disorders and for the development of more effective therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 34252-44-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,2,5 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 34252-44:
(7*3)+(6*4)+(5*2)+(4*5)+(3*2)+(2*4)+(1*4)=93
93 % 10 = 3
So 34252-44-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2O2/c1-11-8(9(12)13)6-4-2-3-5-7(6)10-11/h2-5H,1H3,(H,12,13)
34252-44-3Relevant articles and documents
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Tertov,Onishchenko
, (1970)
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2 -ALKYL- INDAZOLE COMPOUNDS FOR THE TREATMENT OF CERTAIN CNS-RELATED DISORDERS
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Page/Page column 21, (2008/12/05)
2-Alkyl-indazole compound and its pharmaceutically acceptable salts of acid addition, method and intermediates for preparing them, a pharmaceutical composition containing them and use of the latter. The 2-alkyl-indazole compound has the following general formula (I) in which R1, R2, R3, R4, R6, R7, X, Y, W, n, p, and m have the meanings stated in the description.
Indazoles as indole bioisosteres: Synthesis and evaluation of the tropanyl ester and amide of indazole-3-carboxylate as antagonists at the serotonin 5HT3 receptor
Fludzinski,Evrard,Bloomquist,Lacefield,Pfeifer,Jones,Deeter,Cohen
, p. 1535 - 1537 (2007/10/02)
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