109240-67-7Relevant articles and documents
5-Methyl-4H-1,3-dioxins, new chiral building blocks: Transformation into (R)- and (S)-4-hydroxymethyl-4-methyl-1,3-dioxolanes via oxidation and rearrangement and determination of the absolute configuration
Flock, Susanne,Frauenrath, Herbert,Wattenbach, Carsten
, p. 3394 - 3399 (2005)
5-Methyl-4H-1,3-dioxins obtained by asymmetric double-bond isomerization have been transformed into 4-hydroxymethyl-4-methyl-1,3-dioxolanes by m-chloroperbenzoic acid oxidation, ring contraction and reduction. The stereochemical course of this transformat
Enantioselective syntheses of the proposed structures of cytotoxic macrolides iriomoteolide-1a and -1b
Ghosh, Arun K.,Yuan, Hao
supporting information; experimental part, p. 3120 - 3123 (2010/09/16)
(Figure Presented) Enantioselective total syntheses of the proposed structures of macrolide cytotoxic agents iriomoteolide-1a and -1b have been accomplished. The synthesis was carried out in a convergent and stereoselective manner. However, the present wo
An alternative approach to (S)- and (R)-2-methylglycidol O-benzyl ether derivatives
Avenoza, Alberto,Cativiela, Carlos,Peregrina, Jesus M.,Sucunza, David,Zurbano, Maria M.
, p. 1383 - 1388 (2007/10/03)
This report describes the gram scale synthesis of (S)- and (R)-2,2,4-trimethyl-4-(hydroxymethyl)-1,3-dioxolanes using the Sharpless asymmetric dihydroxylation (AD) of the Weinreb amide of 2-methyl-2-propenoic acid. The 2-methylglycerol acetonides resultan
