1093651-96-7 Usage
Description
(2S,4R)-1-(tert-butoxycarbonyl)-4-phenylpyrrolidine-2-carboxylic acid is a pyrrolidine derivative with a molecular formula C17H23NO4. It features a chiral center at carbon atom 2, leading to two possible stereoisomers, with (2S,4R) being the predominant form. (2S,4R)-1-(tert-butoxycarbonyl)-4-phenylpyrrolidine-2-carboxylic acid has a tert-butoxycarbonyl (Boc) protecting group on the nitrogen atom and a carboxylic acid group at position 2, making it a versatile building block in organic synthesis and medicinal chemistry for creating pharmaceuticals and biologically active compounds.
Uses
Used in Organic Synthesis:
(2S,4R)-1-(tert-butoxycarbonyl)-4-phenylpyrrolidine-2-carboxylic acid serves as a key intermediate in organic synthesis, providing a foundation for constructing more complex molecules with specific functionalities.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (2S,4R)-1-(tert-butoxycarbonyl)-4-phenylpyrrolidine-2-carboxylic acid is utilized as a building block for the synthesis of pharmaceuticals. Its unique structure allows for the development of compounds with potential therapeutic applications.
Used in Protecting Groups Strategy:
The Boc protecting group in (2S,4R)-1-(tert-butoxycarbonyl)-4-phenylpyrrolidine-2-carboxylic acid is used to temporarily mask the amino group, enabling selective chemical reactions at other sites within the molecule. This strategy is crucial for the synthesis of complex bioactive compounds where the protection and deprotection of functional groups are necessary steps.
Used in the Synthesis of Biologically Active Compounds:
(2S,4R)-1-(tert-butoxycarbonyl)-4-phenylpyrrolidine-2-carboxylic acid is employed in the creation of biologically active compounds, contributing to the development of new drugs and therapeutic agents with specific targets and mechanisms of action.
Check Digit Verification of cas no
The CAS Registry Mumber 1093651-96-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,3,6,5 and 1 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1093651-96:
(9*1)+(8*0)+(7*9)+(6*3)+(5*6)+(4*5)+(3*1)+(2*9)+(1*6)=167
167 % 10 = 7
So 1093651-96-7 is a valid CAS Registry Number.
1093651-96-7Relevant articles and documents
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
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Page/Page column 1675; 1676, (2016/05/09)
The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
