109801-00-5Relevant articles and documents
Synthesis of highly decorated chiral 2-nitro-cyclohexane carboxylic esters through microwave-assisted organocatalyzed cascade reactions
Massolo, Elisabetta,Benaglia, Maurizio,Parravicini, Davide,Brenna, Davide,Annunziata, Rita
, p. 6639 - 6642 (2014)
Starting from (E)-β-substituted-β-nitroacrylates and α,β-unsaturated ketones, a stereoselective organocatalyzed one-pot methodology allowed to synthesize highly decorated chiral 2-nitro-cyclohexane carboxylic esters. The reaction is promoted by Cinchona a
-
Petrow,Kaplan
, (1949)
-
Evaluation of several fluorinated ATPH derivatives as functionalized Lewis acid receptors for conjugate alkylation to α,β-unsaturated aldehydes with alkyllithium nucleophiles
Ooi, Takashi,Kondo, Yuichiro,Miura, Tomoya,Maruoka, Keiji
, p. 3951 - 3954 (1997)
Several fluorinated aluminum tris(2,6-diphenylphenoxide) (ATPH) derivatives have been synthesized to evaluate, as functionalized Lewis acid receptors, the conjugate alkylation ability to α,β-unsaturated aldehydes by the combined use of alkyllithium nucleo
Catalytic asymmetric addition of aldehydes using organolithium reagents in the presence of commercial available chiral diol ligands
Zong, Hua,Huang, Huayin,Song, Ling
supporting information, p. 1069 - 1074 (2016/10/11)
An efficient method for the catalytic asymmetric additions to aldehydes using organolithium reagents and titanium(IV) isopropoxide in the presence of commercially available and relatively inexpensive diol ligands, such as (S)-BINOL or D-TADDOL has been developed. Good to excellent yields (up to 92%) and enantioselectivities (up to 94%) of the corresponding secondary alcohol products can be obtained following a simple procedure at relatively mild reaction temperatures.
1,n-rearrangement of allylic alcohols promoted by hot water: Application to the synthesis of navenone B, a polyene natural product
Li, Pei-Fang,Wang, Heng-Lu,Qu, Jin
, p. 3955 - 3962 (2014/05/20)
It was reported for the first time that hot water as a mildly acidic catalyst efficiently promoted 1,n-rearrangement (n = 3, 5, 7, 9) of allylic alcohols. In some cases, the rearrangement reactions joined isolated C-C double or triple bonds to generate conjugated polyene or enyne structure motifs. We used the 1,3-rearrangement reaction of an allylic alcohol in hot water as part of an attractive new strategy for construction of the polyene natural product navenone B by iterative use of a Grignard reaction, a 1,3-rearrangement of the resulting allylic alcohol, and subsequent oxidation of the rearranged product.
