11006-56-7 Usage
Description
Pangamic acid, also known as pangamate, is a chemical compound with the empirical formula C10H19O8N and a molecular weight of 281. It was initially promoted by Ernst T. Krebs, Sr. and his son Ernst T. Krebs, Jr. as a medicinal compound for the treatment of a wide range of diseases and was termed "Vitamin B15." However, it is not a true vitamin, has no nutritional value, and has no scientifically verified use in the treatment of any disease. The term "pangamic acid" is more of a label used to describe one of any number of chemical compounds rather than a particular substance.
Uses
Since pangamic acid has not been scientifically verified to have any specific characteristics or applications, there are no established uses for it in any industry. The compound has been called a "quack remedy" and its purported medicinal properties have not been supported by scientific research.
Safety
Positive results from mutagenicity analysis via the Ames test of compounds commonly found in preparations labelled "pangamic acid" including diisopropylamine dichloroacetate, diisopropylamine, dichloroacetate, as well as dimethylglycine mixed with sodium nitrite suggests there may be concern for the development of cancer with the use of these substances.
Clinical claims and research
The Krebses' original patent claimed pangamic acid could be used for detoxification as well as treatment of asthma, skin conditions, joint pain, and nerve pain, with none of these claims supported by evidence in the patent application. Early promotion for pangamic acid included use by race horses as well as humans. Although given the name "Vitamin B15" by the Krebses, there is no evidence that it meets the definition of a vitamin as there is no evidence it is a nutrient needed by the body. Much of the clinical research on pangamic acid took place in the former Soviet Union, though that research often did not describe which of the many compounds called "pangamic acid" was used in the study. This research was also of limited quality due to being overwhelmingly anecdotal in nature ( as opposed to controlled experimentation ) and ignoring short and long term safety in human use. Although more recent claims include treatment of a wide variety of conditions including cancer, heart disease, schizophrenia as well as providing improvement in oxygen utilization, there is no significant evidence for any of these claims or that it is safe for human use. One review noted that it meets "the criteria that define a quack remedy.".
Check Digit Verification of cas no
The CAS Registry Mumber 11006-56-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,1,0,0 and 6 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 11006-56:
(7*1)+(6*1)+(5*0)+(4*0)+(3*6)+(2*5)+(1*6)=47
47 % 10 = 7
So 11006-56-7 is a valid CAS Registry Number.
