110171-24-9

Basic information

• Product Name: 2(5H)-Furanone, 5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-, (5R)-
• CAS NO: 110171-24-9
• Molecular Formula: C21H24O3Si
• Molecular Weight: 352.505
• Mol File: 110171-24-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2(5H)-Furanone, 5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-, (5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Furanone, 5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-, (5R)-(110171-24-9)
• EPA Substance Registry System: 2(5H)-Furanone, 5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-, (5R)-(110171-24-9)

Safety Data

• Hazardous Substances Data: 110171-24-9(Hazardous Substances Data)

Upstream product

• 85428-26-8 (+)-(R)-5-benzyloxymethylfuran-2(5H)-one 
• 1403352-72-6 C₁₁H₁₂O₄S 
• 106757-56-6 (Z)-(-)-methyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate 
• 36326-38-2 ethyl (R,Z)-3-(2′,2′-dimethyl-1′,3′-dioxolan-4′-yl)acrylate 
• 364373-24-0 5-benzyloxymethyl-3-phenylselanyl-dihydrofuran-2-one 
• 364373-27-3 5-benzyloxymethyl-3-phenylsulfanyl-dihydrofuran-2-one 
• 6893-26-1 D-Glutamic acid 
• 52813-63-5 (5R)-2,3,4,5-tetrahydro-5-hydroxymethyl-2-furanone 
• 112837-17-9 (R)-(+)-5-(hydroxymethyl)furan-2(5H)-one 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 1403352-48-6 tert-butyl[(2R,3S,5R)-3-((Z)-2-iodovinyl)-5-methoxytetrahydrofuran-2-ylmethoxy]diphenylsilane 
• 1403352-78-2 (Z)-3-[(2R,3S,5R)-2-(tert-butyldiphenylsilanyloxymethyl)-5-methoxytetrahydrofuran-3-yl]acrylic acid methyl ester 
• 202392-39-0 ((2R,3R,5R)-5-Allyl-3-methyl-tetrahydro-furan-2-ylmethoxy)-tert-butyl-diphenyl-silane 
• 202392-41-4 tert-Butyl-[(2R,3R,5R)-5-(3-methoxymethoxy-propyl)-3-methyl-tetrahydro-furan-2-ylmethoxy]-diphenyl-silane 
• 202392-40-3 3-[(2R,4R,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-methyl-tetrahydro-furan-2-yl]-propan-1-ol 
• 397886-62-3 2,2-Dimethyl-propionic acid 2-[(2S,4R,6S)-6-[(2E,9E)-(6R,7R)-11-hydroxy-6-(4-methoxy-benzyloxy)-7-methyl-undeca-2,9-dien-4-ynyl]-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-ethyl ester 
• 397886-47-4 (E)-(5R,6R)-6-(4-Methoxy-benzyloxy)-5-methyl-oct-2-en-7-yn-1-ol 
• 529495-84-9 N-benzoyl-1-[2',3'-dideoxy-3'-C-tris(methylthio)methyl-β-L-erythro-pentofuranosyl]cytosine-5'-(2-cyanoethyl hexadecyl phosphate) 
• 529495-82-7 N-benzoyl-1-[5'-O-tert-butyldiphenylsilyl-2',3'-dideoxy-3'-C-tris(methylthio)methyl-β-L-erythro-pentofuranosyl]cytosine 
• 529495-88-3 1-[5'-O-tert-butyldiphenylsilyl-2',3'-dideoxy-3'-C-tris(methylthio)methyl-β-L-erythro-pentofuranosyl]thymine 
• 529495-87-2 1-[5'-O-tert-butyldiphenylsilyl-2',3'-dideoxy-3'-C-tris(methylthio)methyl-β-L-erythro-pentofuranosyl]-5-fluorouracil 
• 529495-89-4 1-[5'-O-tert-butyldiphenylsilyl-2',3'-dideoxy-3'-C-tris(methylthio)methyl-β-L-erythro-pentofuranosyl]cytosine 
• 529495-79-2 1-[5'-O-tert-butyldiphenylsilyl-2',3'-dideoxy-3'-C-tris(methylthio)methyl-β-L-erythro-pentofuranosyl]uracil 
• 529495-78-1 (4R,5R)-5-{[(tert-butyldiphenylsilyl)oxy]methyl}-4-[tri(methylthio)methyl]tetrahydrofuran-2-yl acetate 

Relevant articles and documents

Total synthesis of branimycin: An evolutionary approach

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A tether controlled exo-selective trans-annular Diels - Alder (TADA) reaction

A fully substrate controlled stereoselective route to construct cis-hexahydronaphthalene 4 is described starting from nonracemic butenolide 6. The key step is an exo-selective transannular Diels-Alder reaction (TADA) of tetraene 5, whose intrinsic constra

Convenient new syntheses of R-(+)-5-benzyloxymethyl-5H-furan-2-one- a building block en route to L-nucleosides

R-(+)-5-Benzyloxymethyl-5H-furan-2-one (R-(1)) was obtained from commercially available R-(-)-2-benzyloxymethyl oxirane (R-(2)) in two and three steps, respectively. Key steps are a) the nucleophilic ring opening of the oxirane moiety with dianions derived from either PhSeCH2CO2H or PhSCH2CO2H; b) oxidation to the corresponding 1-oxides and c) concomitant or thermally induced syn-elimination. R-(1) was obtained with ≥97% ee and ≥95% ee, respectively.