36326-38-2

Basic information

• Product Name: (E)-3-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-ACRYLIC ACID ETHYL ESTER
• Synonyms: (E)-3-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-ACRYLIC ACID ETHYL ESTER;(R,E)-ETHYL 3-(2,2-DIMETHYL-1,3-DIOXOLAN-4-YL)ACRYLATE;(1R,4R)-METHYL 4-(HYDROXYMETHYL)CYCLOHEXANECARBOXYLATE(WXC08504)
• CAS NO: 36326-38-2
• Molecular Formula: C₁₀H₁₆O₄
• Molecular Weight: 200.23164
• Mol File: 36326-38-2.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 241.0±0.0 °C(Predicted)
• Appearance: /
• Density: 1.102±0.06 g/cm3(Predicted)
• CAS DataBase Reference: (E)-3-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-ACRYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-ACRYLIC ACID ETHYL ESTER(36326-38-2)
• EPA Substance Registry System: (E)-3-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-ACRYLIC ACID ETHYL ESTER(36326-38-2)

Safety Data

• Hazardous Substances Data: 36326-38-2(Hazardous Substances Data)

Usage

Description

(E)-3-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-ACRYLIC ACID ETHYL ESTER, with the molecular formula C10H16O4, is a chemical compound that features an ethyl ester of acrylic acid and a dioxolane ring in its structure. This colorless liquid with a characteristic odor is utilized in various industrial applications and organic synthesis processes.

Uses

Used in Polymer Production:
(E)-3-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-ACRYLIC ACID ETHYL ESTER is used as a monomer for the production of polymers, contributing to the development of materials with specific properties tailored for various applications.
Used in Adhesives Industry:
In the adhesives industry, (E)-3-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-ACRYLIC ACID ETHYL ESTER is used as a component in formulating adhesives, enhancing their bonding capabilities and performance characteristics.
Used in Coatings Industry:
(E)-3-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-ACRYLIC ACID ETHYL ESTER is used as a key ingredient in the coatings industry, improving the durability, adhesion, and overall quality of the final product.
Used in Organic Synthesis:
(E)-3-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-ACRYLIC ACID ETHYL ESTER is used as a reagent in organic synthesis, playing a crucial role in the creation of other organic compounds and contributing to the advancement of chemical research and development.
Used in Building Blocks for Synthesis:
(E)-3-(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-ACRYLIC ACID ETHYL ESTER also serves as a building block for the synthesis of other organic compounds, expanding the possibilities for chemical innovation and the creation of novel materials and substances.

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 22323-80-4 (4S)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 14347-78-5 1,2-O-isopropylidene-D-glycerol 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 84379-53-3 2-O-benzyl-3,4-O-isopropylidene-L-threitol 
• 50-81-7 ascorbic acid 
• 1128-23-0 L-gulono-1,4-lactone 
• 56710-46-4 L-5,6-isopropylidene-gulono-1,4-lactone 
• 64870-23-1 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 15042-01-0 5,6-O-isopropylidene-L-ascorbic acid 
• 24074-26-8 ethyl (diisopropylphosphoryl)acetate 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 70223-09-5 [(4R,5R)-5-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-1,3-dioxolan-4-yl]methanol 

Downstream Products

• 78508-96-0 (5S)-5-(hydroxymethyl)-5H-furan-2-one 
• 81703-93-7 methyl (2E)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate 
• 51268-87-2 (4S)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)propan-1-ol 
• 105865-97-2 Ethyl 4,5-O-isopropylidene-(3R/S,4S)-4,5-dihydroxy-3-phenylthiopentanoate 
• 105865-98-3 Ethyl 4,5-O-isopropylidene-(3S,4S)-4,5-dihydroxy-3-phenylthiopentanoate 
• 105865-97-2 Ethyl 4,5-O-isopropylidene-(3R,4S)-4,5-dihydroxy-3-phenylthiopentanoate 
• 210548-97-3 (R)-3-{3-[Benzyl-(3-cyano-propyl)-amino]-propylamino}-3-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-propionic acid ethyl ester 
• 112837-17-9 (R)-(+)-5-(hydroxymethyl)furan-2(5H)-one 
• 79060-23-4 (2E)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-en-1-ol 
• 80532-35-0 (2Z)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-en-1-ol 
• 866594-60-7 (3aS,4S,6aR)-4-methoxy-tetrahydro-furo[3.4-b]furan-2(3H)-one 
• 156928-09-5 (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol 
• 1265592-08-2 (2S,3R)-tert-butyl 2-(benzyloxy)-3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)pent-4-enoate 
• 1265592-11-7 (2R,3R)-1-tert-butoxy-3-((4R)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-oxopent-4-en-2-yl-4-nitrobenzoate 

Relevant articles and documents

MONOBACTAM COMPOUNDS AND USE THEREFOR

Monobactam compounds and a use therefor. Specifically provided are chemical compounds represented by formula (I) or isomers, pharmaceutically acceptable salts, solvates, crystals, or prodrugs thereof, preparation methods therefor, pharmaceutical compositions containing said compounds, and a use of said compounds or compositions in treating bacterial infection. The present compounds feature excellent antibacterial activity, and have great hopes of becoming a therapeutic agent for bacterial infection.

Stereoselective synthesis and antiproliferative activity of the isomeric sphinganine analogues

A flexible synthetic approach to biologically active sphingoid base-like compounds with a 3-amino-1,2-diol framework was achieved through a [3,3]-sigmatropic rearrangement and late stage olefin cross-metathesis as the key transformations. The stereochemistry of the newly created stereogenic centre was assigned via a single crystal X-ray analysis of the (4S,5R)-5-(hydroxymethyl)-4-vinyloxazolidine-2-thione. In order to rationalise the observed stereoselectivity of the aza-Claisen rearrangement, DFT calculations were carried out. The targeted isomeric sphingoid bases were screened in vitro for anticancer activity on a panel of seven human malignant cell lines. Cell viability experiments revealed that C17-homologues are more active than their C12 congeners.

PROCESS FOR THE PREPARATION OF [(1 S,2R)-3-[[(4-AMINOPHENYL)SULFONYL] (2-METHYLPROPYL)AMINO]-2-HYDROXY-1 -(PHENYLMETHYL)PROPYL]-CARBAMIC ACID (3R,3AS,6AR)HEXAHYDRO FURO[2,3-B]FURAN-3-YL ESTER AND ITS AMORPHOUS FORM

The present invention relates to an improved process for the preparation of [(1 S,2R)-3-[ [(4-aminophenyl)sulfonyl] (2-methylpropyl)amino]-2-hydroxy- 1 -(phenylmethyl)propyl] - carbamic acid (3R,3aS,6aR)hexahydrofuro[2,3-b]furan-3-yl ester compound of formula- 1 represented by the following structural formula: