110397-80-3

Basic information

• Product Name: (E)-α-(3,4,5-trimethoxybenzylidene)-β-(3,4,5-trimethoxybenzyl)-γ-butyrolactone
• Synonyms: (E)-α-(3,4,5-trimethoxybenzylidene)-β-(3,4,5-trimethoxybenzyl)-γ-butyrolactone
• CAS NO: 110397-80-3
• Molecular Weight: 444.482
• Mol File: 110397-80-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-α-(3,4,5-trimethoxybenzylidene)-β-(3,4,5-trimethoxybenzyl)-γ-butyrolactone(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-α-(3,4,5-trimethoxybenzylidene)-β-(3,4,5-trimethoxybenzyl)-γ-butyrolactone(110397-80-3)
• EPA Substance Registry System: (E)-α-(3,4,5-trimethoxybenzylidene)-β-(3,4,5-trimethoxybenzyl)-γ-butyrolactone(110397-80-3)

Safety Data

• Hazardous Substances Data: 110397-80-3(Hazardous Substances Data)

Upstream product

• 65171-10-0 (+/-)-4-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2(3H)-furanone 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 76763-88-7 (R)-dihydro-4-(3,4,5-trimethoxybenzyl)furan-2(3H)-one 
• 84736-30-1 (trimethoxy-3,4,5 benzylidene) α-hemisuccinate de methyle 
• 119138-93-1 (+/-)-4-(3,4,5-trimethoxyphenyl)-3-methoxycarbonylbutanoic acid 

Downstream Products

• 7432-28-2 isoschizandrin 
• 93395-16-5 (3S*,4R*)-3-(3,4,5-trimethoxybenzyl)-4-(3,4,5-trimethoxybenzyl)-4,5-dihydro-2(3H)-furanone 
• 93395-16-5 (3R*,4R*)-3-(3,4,5-trimethoxybenzyl)-4-(3,4,5-trimethoxybenzyl)-4,5-dihydro-2(3H)-furanone 
• 145432-30-0 3,4-Bis-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one 
• 117407-00-8 2,3-bis(3,4,5-trimethoxybenzyl)-4-butanolide 

Relevant articles and documents

Simple synthesis of trans-α,β-dibenzyl-γ-butyrolactone lignans by diastereoselective reduction of α-benzylidene-β-benzyl-γ-butyralactones using NaBH4-NiCl2

trans-α,β-Dibenzyl-γ-butyrolactone lignans were synthesized by stereoselective reduction of α-benzylidene-β-benzyl-γ-butyrolactones using NaBH4-NiCl2. The reduction is found to proceed via conjugate addition of a hydride to an α-benz

Ruthenium dioxide in fluoro acid medium: I. A new agent in the biaryl oxidative coupling. Application to the synthesis of non phenolic bisbenzocyclooctadiene lignan lactones

Ruthenium (IV) dioxide dihydrate in fluoro acid medium was found to be a very efficient agent for the oxidative coupling of non phenolic lignans and their derivatives, and this method was applied to the total synthesis of (+/-)-neoisostegane 2a and (+/-)-steganolide A 2b. This procedure was also used to obtain the first stereospecific synthesis of a cis-bisbenzocyclooctadiene lactone, the (+/-)-deoxyschizandrin 17, of which, was afforded by a short reduction sequence.