110715-84-9Relevant articles and documents
Synthesis of (+/-)-Hernandulcin by an Intramolecular Nitrile Oxide Cycloaddition Route from Farnesol
Zheng, Guo-Chi,Kakisawa, Hiroshi
, p. 602 - 604 (1989)
An intramolecular addition reaction of the nitrile oxide derived from (2Z,6E)-farnesal oxime afforded an isoxazoline derivative, which was converted into hernandulcin, a sweet sesquiterpene of Verbenaceae plant.
SYNTHESIS OF (6S,1'S)-(+)-HERNANDULCIN, A SWEETNER, AND ITS STEREOISOMERS
Mori, Kenji,Kato, Minoru
, p. 5895 - 5900 (2007/10/02)
All of the four possible stereoisomers of hernandulcin were synthesized starting from the enantiomers of limonene.The absolute configuration of the naturally occuring and sweet-tasting (+)-hernandulcin was established as 6S,1'S.Other stereoisomers were not sweet at all.