1113025-23-2 Usage
Description
[(1S,3S,5S)-3-(Tritylamino)-6-oxabicyclo[3.1.0]hexan-1-yl]methanol, also known as Tritylamine, is a chemical compound with the molecular formula C24H25NO. It is a white to off-white solid substance that is used in organic synthesis as a protecting group for alcohols. Tritylamine is known for its ability to form stable complexes with various acids, making it a useful reagent in organic chemistry. It is commonly employed in the synthesis of peptides and nucleotides, where it acts as a protective agent for the hydroxyl groups. Tritylamine can also be used as a reagent in the synthesis of various pharmaceutical compounds and other organic materials.
Uses
Used in Organic Synthesis:
Tritylamine is used as a protecting group for alcohols in organic synthesis. Its application is due to its ability to form stable complexes with various acids, which helps in protecting the hydroxyl groups during the synthesis process.
Used in Pharmaceutical Compounds Synthesis:
Tritylamine is used as a reagent in the synthesis of various pharmaceutical compounds. Its application is attributed to its stability and reactivity, which are essential for the development of new drugs and medications.
Used in Peptide and Nucleotide Synthesis:
Tritylamine is used as a protective agent for the hydroxyl groups in the synthesis of peptides and nucleotides. Its application is due to its ability to form stable complexes, which is crucial for the successful synthesis of these biologically important molecules.
Used in Chemical Research:
Tritylamine is used as a reagent in chemical research, particularly in the study of organic reactions and the development of new synthetic methods. Its application is based on its reactivity and stability, which are important for understanding and optimizing chemical reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 1113025-23-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,1,3,0,2 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1113025-23:
(9*1)+(8*1)+(7*1)+(6*3)+(5*0)+(4*2)+(3*5)+(2*2)+(1*3)=72
72 % 10 = 2
So 1113025-23-2 is a valid CAS Registry Number.
1113025-23-2Relevant articles and documents
Process Development and GMP Production of a Potent NAE Inhibitor Pevonedistat
Armitage, Ian,Elliott, Eric L.,Hicks, Frederick,Langston, Marianne,McCarron, Ashley,McCubbin, Quentin J.,Obrien, Erin,Stirling, Matt,Zhu, Lei
, p. 1299 - 1307 (2015/09/28)
A practical synthesis of a novel NEDD8-activating enzyme (NAE) inhibitor pevonedistat (MLN4924) is described. Key steps include an enantioselective synthesis of an amino-diol cyclopentane intermediate containing three chiral centers and a novel, regiosele
