111853-20-4

Basic information

• Product Name: 9H-Purin-6-amine, 9-(1-methylethyl)-N-(phenylmethyl)-
• CAS NO: 111853-20-4
• Molecular Formula: C15H17N5
• Molecular Weight: 267.333
• Mol File: 111853-20-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 9H-Purin-6-amine, 9-(1-methylethyl)-N-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 9H-Purin-6-amine, 9-(1-methylethyl)-N-(phenylmethyl)-(111853-20-4)
• EPA Substance Registry System: 9H-Purin-6-amine, 9-(1-methylethyl)-N-(phenylmethyl)-(111853-20-4)

Safety Data

• Hazardous Substances Data: 111853-20-4(Hazardous Substances Data)

Upstream product

• 1214-39-7 6-benzyladenine 
• 75-26-3 isopropyl bromide 

Relevant articles and documents

ALKYLATION OF SOME 6-SUBSTITUTED PURINES UNDER INTERPHASE CATALYSIS CONDITIONS

The mixture of 9-, 3-, and 7-benzyl-6-substituted purines is formed in almost quantitative yield by the alkylation of 6-benzylamino-, 6-furfurylamino-, 6-methylthio-, and 6-chloropurine with benzyhalides in the biphasic system of the liquid-liquid or liquid-solid type in the presence of interphase catalysts (quarternary ammonium salts, 18-crown-6).The catalytic activity of the quarternary ammonium salts increases with the inrease in the lipophilicity of the cation.Taking the alkylation of 6-benzylaminopurine as an example, the possibility of the application of ''triphasic catalysis'' in the alkylation reaction of purines is indicated.The alkylation of 6-substituted purines with isopropylbromide proceeds regioselectively under the conditions of the interphase catalysis with the formation of the corresponding 9-isopropylpurines.