1120-49-6

Basic information

• Product Name: DIDECYLAMINE
• Synonyms: 1-Decanamine, N-decyl-;1-Decanamine,N-decyl-;Armeen 2-10;N,N-Didecylamine;n-decyl-1-decanamin;N-decyl-1-Decanamine;Radiamine 6310;DI-N-DECYLAMINE
• CAS NO: 1120-49-6
• Molecular Formula: C₂₀H₄₃N
• Molecular Weight: 297.56
• EINECS: 214-312-1
• Product Categories: Amines;C11 to C38;Nitrogen Compounds
• Mol File: 1120-49-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: 38-40 °C(lit.)
• Boiling Point: 179-180 °C2 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: white solid
• Density: 0.7963 (estimate)
• Vapor Pressure: 9.56E-06mmHg at 25°C
• Refractive Index: 1.4552 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly) , Hexanes (Slightly)
• PKA: 10.87±0.19(Predicted)
• Stability: Stable. Combustible. Incompatible with oxidizing agents.
• BRN: 1763492
• CAS DataBase Reference: DIDECYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: DIDECYLAMINE(1120-49-6)
• EPA Substance Registry System: DIDECYLAMINE(1120-49-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: 2735
• WGK Germany: 3
• F: 10-34
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 1120-49-6(Hazardous Substances Data)

Usage

Description

DIDECYLAMINE is a white solid that serves as a nitrogen-containing organic building block. It is known for its role in the growth of gram-negative Pseudomonas sp bacteria, which are sourced from activated sludge.

Uses

Used in Chemical Synthesis:
DIDECYLAMINE is used as a building block in the chemical synthesis industry for its nitrogen-containing properties, which contribute to the formation of various organic compounds.
Used in Microbiology:
In the field of microbiology, DIDECYLAMINE is utilized as a substrate for the growth of gram-negative Pseudomonas sp bacteria. This application aids in the study and understanding of these bacteria, which are commonly found in activated sludge.

Purification Methods

Dissolve the amine in *benzene and precipitate it as its bisulfate by shaking with 4M H2SO4. Filter, wash with *benzene, separate by centrifugation, then the free base is obtained by treating with NaOH [McDowell & Allen J Phys Chem 65 1358 1961]. It is a strong base; store away from CO2. [Beilstein 4 IV 780.]

InChI:InChI=1/C20H43N/c1-3-5-7-9-11-13-15-17-19-21-20-18-16-14-12-10-8-6-4-2/h21H,3-20H2,1-2H3

Upstream product

• 2319-29-1 decanamide 
• 1002-69-3 decyl chloride 
• 2016-57-1 1-aminodecane 
• 65588-59-2 4-Nitro-benzolsulfonsaeure-decylamid 
• 621-71-6 capric acid triglyceride 
• 1975-78-6 n-decanenitrile 
• 112-29-8 1-bromo dodecane 
• 112-53-8 1-dodecyl alcohol 
• 124-22-1 n-Dodecylamine 
• 112-30-1 1-Decanol 
• 112-31-2 caprinaldehyde 
• 7664-41-7 ammonia 
• 91-17-8 decalin 
• 108-38-3 m-xylene 

Downstream Products

• 5422-42-4 N,N-bis-decyl-lactamide 
• 86781-48-8 1,1-di-(n-decyl)-3-(2,4-dimethylphenyl)urea 
• 62984-52-5 2-didecylaminomethylphenol 
• 1242056-29-6 bis(4-didecylamino-2,6-dimethoxyphenyl)(2,6-dimethoxyphenyl)methylium hexafluorophosphate 
• 1242056-11-6 (4-didecylamino-2,6-trimethoxyphenyl)(2,6-dimethoxyphenyl)-(2,4,6-trimethoxyphenyl)methylium hexafluorophosphate 
• 1242056-23-0 (4-didecylamino-2,6-dimethoxyphenyl)bis(2,6-dimethoxyphenyl)methylium hexafluorophosphate 
• 1613714-16-1 4-didecylamino-2,6-dimethoxyphenyl-bis(4-dimethylamino-2,6-trimethoxyphenyl)carbenium chloride 
• 2486-84-2 di-n-decylammonium chloride 
• 7460-23-3 1-(4-chloro-[1]naphthyl)-2-didecylamino-ethanol 
• 7396-58-9 N-methyldidecylamine 

Relevant articles and documents

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Serum Compatible Spermine-Based Cationic Lipids with Nonidentical Hydrocarbon Tails Mediate High Transfection Efficiency

Cationic lipids are widely used as nonviral synthetic vectors for gene delivery as a safer alternative to viral vectors. In this work, a library of L-shaped spermine-based cationic lipids with identical and nonidentical hydrophobic chains having variable carbon lengths (from C10 to C18) was designed and synthesized. These lipids were characterized and the structure-activity relationships of these compounds were determined for DNA binding and transfection ability when formulated as cationic liposomes. The liposomes were then used successfully for the transfection of HEK293T, HeLa, PC3, H460, HepG2, SH-SY5Y and Calu’3 cell lines. The transfection efficiency of lipids with nonidentical hydrocarbon chains was greater than the identical analogue. These reagents exhibited superior efficiency to the commercial reagent, Lipofectamine3000, under both serum-free and 10–40 % serum conditions in HEK293T, HeLa and H460 cell lines. The lipids were not toxic to the tested cell line. The results suggest that L-shaped spermine-based cationic lipids with nonidentical hydrocarbon tails could serve as efficient and safe nonviral vector gene carriers in further in vivo studies.

Selective Transformations of Triglycerides into Fatty Amines, Amides, and Nitriles by using Heterogeneous Catalysis

The use of triglycerides as an important class of biomass is an effective strategy to realize a more sustainable society. Herein, three heterogeneous catalytic methods are reported for the selective one-pot transformation of triglycerides into value-added chemicals: i) the reductive amination of triglycerides into fatty amines with aqueous NH3 under H2 promoted by ZrO2-supported Pt clusters; ii) the amidation of triglycerides under gaseous NH3 catalyzed by high-silica H-beta (Hβ) zeolite at 180 °C; iii) the Hβ-promoted synthesis of nitriles from triglycerides and gaseous NH3 at 220 °C. These methods are widely applicable to the transformation of various triglycerides (C4–C18 skeletons) into the corresponding amines, amides, and nitriles.

COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS

The disclosure features amino lipids and compositions involving the same. Nanoparticle compositions include an amino lipid as well as additional lipids such as phospholipids, structural lipids, PEG lipids, or a combination thereof. Nanoparticle compositions further including therapeutic and/or prophylactic agents such as RNA are useful in the delivery of therapeutic and/or prophylactic agents to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.