7396-58-9

Basic information

• Product Name: N-Methyldidecylamine
• Synonyms: DAMA-10;DIDECYLMETHYLAMINE;DI-N-DECYLMETHYLAMINE;C1010 DAMA(R) AMINE;C1010 DIAKLYMETHYLAMINE;N-METHYLDIDECYLAMINE;n-decyl-n-methyl-1-decanamin;N-decyl-N-methyl-1-Decanamine
• CAS NO: 7396-58-9
• Molecular Formula: C₂₁H₄₅N
• Molecular Weight: 311.59
• EINECS: 230-990-1
• Product Categories: Amines;Building Blocks;C17 to C40+;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 7396-58-9.mol
• Article Data: 14

Chemical Properties

• Melting Point: -7.4 °C
• Boiling Point: 145 °C / 2mmHg
• Flash Point: 93°C
• Appearance: clear slightly light yellow liquid with a fishlike odor
• Density: 0.807 g/mL at 20 °C(lit.)
• Vapor Pressure: 1.6E-05mmHg at 25°C
• Refractive Index: n20/D 1.448
• PKA: 9.83±0.50(Predicted)
• Water Solubility: 1.2μg/L
• BRN: 1765810
• CAS DataBase Reference: N-Methyldidecylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Methyldidecylamine(7396-58-9)
• EPA Substance Registry System: N-Methyldidecylamine(7396-58-9)

Safety Data

• RIDADR: UN 2735 8/PG 3
• WGK Germany: 2
• F: 9-34
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 7396-58-9(Hazardous Substances Data)

Usage

Uses

N-?Methyldidecylamine is a reagent used in the synthesis of novel anthraquinone compounds which act as potential anticancer compounds.

General Description

A clear slightly light yellow liquid with a fishlike odor. Insoluble in water and less dense than water. Hence floats on water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion, inhalation or skin absorption. Used to make other chemicals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

DIDECYLMETHYL AMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

InChI:InChI=1/C21H45N/c1-4-6-8-10-12-14-16-18-20-22(3)21-19-17-15-13-11-9-7-5-2/h4-21H2,1-3H3

Upstream product

• 50-00-0 formaldehyd 
• 64-18-6 formic acid 
• 1120-49-6 didecylamine 
• 23220-25-9 N-methyldecanoic acid amide 
• 334-48-5 1-decanoic acid 
• 2016-57-1 1-aminodecane 
• 112-30-1 1-Decanol 
• 74-89-5 methylamine 
• 14433-76-2 N,N-dimethyldecanamide 
• 67-56-1 methanol 
• 112-13-0 n-decanoyl chloride 

Downstream Products

• 7173-51-5 didecyldimethylammonium chloride 

Relevant articles and documents

Synthesis process of dialkyl dimethyl ammonium chloride

The invention discloses a synthesis process of dialkyl dimethyl ammonium halide, which comprises the following steps: mixing primary alkyl halide R1X and long-chain alkyl dimethylamine R2(CH3)2N, heating to 130-150 DEG C in a closed container, keeping the temperature to react for 4-6 hours, cooling, and diluting with an ethanol water solution to obtain dialkyl dimethyl ammonium halide, wherein thereaction temperature is determined by the number of carbon atoms of R1 and R2, and the formula is 130 DEG C+2.5(CR1+CR216)DEG C. Primary alkyl halide and long-chain alkyl dimethylamine directly reactto generate dialkyl dimethyl ammonium halide, so that the use of flammable and combustible gaseous raw materials is avoided, and the production safety is improved, the production process flow and equipment are simple, the production cost is low, industrial popularization is facilitated, no acid or salt byproduct is generated, and the product is high in purity, free of three wastes and environmentally friendly.

Commercial Pd/C-Catalyzed N-Methylation of Nitroarenes and Amines Using Methanol as Both C1 and H2 Source

Herein, we report commercially available carbon-supported-palladium (Pd/C)-catalyzed N-methylation of nitroarenes and amines using MeOH as both a C1 and a H2 source. This transformation proceeds with high atom-economy and in an environmentally friendly way via borrowing hydrogen mechanism. A total of >30 structurally diverse N-methylamines, including bioactive compounds, were selectively synthesized with isolated yields of up to 95%. Furthermore, selective N-methylation and deuteration of nimesulide, a nonsteroidal anti-inflammatory drug, were realized through the late-stage functionalization.

TERTIARY AMINE PREPARATION PROCESS

The present invention relates to a process for producing a tertiary amine, including the following steps (1) and (2): Step (1); introducing an alcohol having 1 to 36 carbon atoms and a raw amine represented by the following general formula (I) into a first reaction vessel to react with each other in the presence of a catalyst and hydrogen, and then continuing the reaction while discharging water produced in the reaction and a hydrogen-containing gas out of a reaction system in the first reaction vessel: R1R2NH??(I) wherein R1 and R2 are each independently a hydrogen atom or a hydrocarbon group having 1 to 36 carbon atoms; and Step (2): introducing the hydrogen-containing gas discharged from the first reaction vessel into a second reaction vessel to reduce an amount of carbon monoxide contained in the hydrogen-containing gas, and then introducing a part or whole of the hydrogen-containing gas into the first reaction vessel.