112392-65-1

Basic information

• Product Name: Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (R)-
• CAS NO: 112392-65-1
• Molecular Formula: C10H19NO4
• Molecular Weight: 217.265
• Mol File: 112392-65-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (R)-(112392-65-1)
• EPA Substance Registry System: Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (R)-(112392-65-1)

Safety Data

• Hazardous Substances Data: 112392-65-1(Hazardous Substances Data)

Upstream product

• 33900-24-2 N-(tert-butoxycarbonyl)-L-methionine methyl ester 
• 917-54-4 methyllithium 
• 56926-94-4 methyl (2S)-2-[N-(t-butoxycarbonyl)amino]-3-(4-methylbenzenesulfonyl)-oxypropionate 
• 93267-04-0 N-(tert-butoxycarbonyl)-L-3-iodoalanine methyl ester 
• 34306-42-8 Boc-Abu 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 74-88-4 methyl iodide 
• 2488-15-5 N-tert-butoxycarbonyl-L-methionine 
• 56776-41-1 methyl 2-(N-(1,1-dimethylethoxy)methanamido)butenoate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 7682-18-0 (S)-2-aminobutyric acid methyl ester hydrochloride 
• 58561-08-3 methyl N-(tert-butoxycarbonyl)-2-aminobutyrate 
• 67-56-1 methanol 
• 63658-16-2 (Z)-methyl 2-((tertbutoxycarbonyl)amino)but-2-enoate 

Downstream Products

• 1158971-61-9 1,1-dimethylethyl {(1S)-1-[bis(4-fluorophenyl)(hydroxy)methyl]propyl}carbamate 
• 98259-91-7 (Z)-1-amino-2-methylcyclopropanecarboxylic acid methyl ester hydrochloride 
• 56776-41-1 (E)-2-N-(tert-butyloxycarbonyl)dehydroaminobutyric acid methyl ester 
• 63658-16-2 (Z)-methyl 2-((tertbutoxycarbonyl)amino)but-2-enoate 
• 622841-46-7 [(E)-(S)-1-Ethyl-4-(4-methoxy-phenyl)-2-oxo-but-3-enyl]-carbamic acid tert-butyl ester 
• 622841-07-0 [(E)-(S)-1-Ethyl-2-hydroxy-4-(4-methoxy-phenyl)-but-3-enyl]-carbamic acid tert-butyl ester 
• 622841-06-9 ((E)-(S)-1-Ethyl-2-hydroxy-4-phenyl-but-3-enyl)-carbamic acid tert-butyl ester 
• 622841-45-6 ((E)-(S)-1-Ethyl-2-oxo-4-phenyl-but-3-enyl)-carbamic acid tert-butyl ester 
• 34306-42-8 Boc-Abu 
• 158009-88-2 (R)-3-[(S)-3-Benzyloxy-2-((S)-2-tert-butoxycarbonylamino-butyrylamino)-propionylamino]-3-phenyl-propionic acid methyl ester 

Relevant articles and documents

APPROACHES TOWARD THE TOTAL SYNTHESES OF ASTIN A, B, AND C

Two nonessential amino acids, (+)-(S)-2-aminobutanoic acid and the methyl ester of L-β-phenylalanine , were synthesized to provide a tripeptide which will be used in the total syntheses of astins A, B, and C.

N-1 BRANCHED CYCLOALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS

lmidazo[4,5-c]quinoline compounds of formula (II) having a substituent that is attached at the N-l position by a branched group, single enantiomers of the compounds, pharmaceutical compositions containing the compounds, and methods of making the compounds

MaxPHOS ligand: PH/NH tautomerism and rhodium-catalyzed asymmetric hydrogenations

MaxPHOS is an active and robust P-stereogenic ligand for asymmetric catalysis. The presence of an -NH- bridge between the two phosphine moieties allows the NH/PH tautomerism to take place. The neutral ligand, in which the NH form predominates, is an air-sensitive compound. However, protonation of MaxPHOS leads to the stable PH form of the ligand, in which the overall positive charge is distributed on both P centers. This protonation turns the MaxPHOS×HBF4 salt 3 into an air-stable compound both in the solid state and in solution. The salt 3 is also a convenient precursor for the preparation of rhodium(I) complexes by direct ligand exchange with the complex [Rh(acac)(cod)]. Finally, the corresponding rhodium(I)-MaxPHOS complex was tested in the asymmetric hydrogenation of a wide range of substrates. The complex proved to be a highly selective and robust system in these reactions.