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63658-16-2

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63658-16-2 Usage

General Description

(Z)-Methyl 2-(tert-butoxycarbonylamino)but-2-enoate, also known as (Z)-Boc-2-amino-2-butenoic acid methyl ester, is a chemical compound commonly used in the synthesis of peptides and other organic molecules. It is a derivative of the amino acid serine, and is often used as a building block in peptide chemistry. The tert-butoxycarbonyl (Boc) protecting group is commonly used to protect the amino group of serine, and the methyl ester group is often used to protect the carboxylic acid group. (Z)-methyl 2-(tert-butoxycarbonylamino)but-2-enoate is valuable in the field of organic synthesis and pharmaceutical research, as it allows for the selective introduction of amino acid residues into peptide and protein structures.

Check Digit Verification of cas no

The CAS Registry Mumber 63658-16-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,6,5 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 63658-16:
(7*6)+(6*3)+(5*6)+(4*5)+(3*8)+(2*1)+(1*6)=142
142 % 10 = 2
So 63658-16-2 is a valid CAS Registry Number.

63658-16-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (Z)-Methyl 2-(tert-butoxycarbonylamino)but-2-enoate

1.2 Other means of identification

Product number -
Other names Methyl (2Z)-2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-2-buten oate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:63658-16-2 SDS

63658-16-2Relevant articles and documents

Catalytic, contra-Thermodynamic Positional Alkene Isomerization

Occhialini, Gino,Palani, Vignesh,Wendlandt, Alison E.

supporting information, p. 145 - 152 (2022/01/19)

The positional isomerization of C═C double bonds is a powerful strategy for the interconversion of alkene regioisomers. However, existing methods provide access to thermodynamically more stable isomers from less stable starting materials. Here, we report

Preclinical Optimization of gp120 Entry Antagonists as anti-HIV-1 Agents with Improved Cytotoxicity and ADME Properties through Rational Design, Synthesis, and Antiviral Evaluation

Curreli, Francesca,Ahmed, Shahad,Benedict Victor, Sofia M.,Iusupov, Ildar R.,Belov, Dmitry S.,Markov, Pavel O.,Kurkin, Alexander V.,Altieri, Andrea,Debnath, Asim K.

, p. 1724 - 1749 (2020/03/10)

We previously reported a milestone in the optimization of NBD-11021, an HIV-1 gp120 antagonist, by developing a new and novel analogue, NBD-14189 (Ref1), which showed antiviral activity against HIV-1HXB2, with a half maximal inhibitory concentr

Npys-Mediated Elimination Reactions of Alcohols and Thiols: A Facile Route to Dehydroalanine and Dehydrobutyrine Building Blocks

Olsen, Frank N.,Tsakos, Michail,Poulsen, Thomas B.

supporting information, p. 2697 - 2701 (2015/11/27)

We report a new and rapid method for side-chain dehydration/dehydrothiolation of serine, threonine, and cysteine building blocks. The method relies on activation with 3-nitro-2-pyridinesulfenyl chloride (Npys-Cl) followed by treatment with base. It is pos

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