112403-88-0

Basic information

• Product Name: Benzenepropanamide, N-methoxy-N-phenyl-
• CAS NO: 112403-88-0
• Molecular Formula: C16H17NO2
• Molecular Weight: 255.316
• Mol File: 112403-88-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenepropanamide, N-methoxy-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamide, N-methoxy-N-phenyl-(112403-88-0)
• EPA Substance Registry System: Benzenepropanamide, N-methoxy-N-phenyl-(112403-88-0)

Safety Data

• Hazardous Substances Data: 112403-88-0(Hazardous Substances Data)

Upstream product

• 91523-31-8 O-methyl N-chloro-3-phenylpropanohydroxamate 
• 112403-99-3 potassium cinnamohydroxamate 
• 112404-04-3 O-methyl cinnamohydroxamate 
• 23601-49-2 O-methyl 3-phenylpropanohydroxamate 

Downstream Products

• 65690-71-3 N-(1-phenylpropionyl)-N-phenylhydroxylamine 
• 152189-75-8 N-(2-hydroxyphenyl)-3-phenylpropanamide 
• 126545-09-3 N-(2-methoxyphenyl)-3-phenylpropanamide 

Relevant articles and documents

N-ALKOXY-N-ACYLNITRENIUM IONS IN INTRAMOLECULAR AROMATIC ADDITION REACTIONS

N-alkoxy-N-acylnitrenium ions are generated by treatment of N-alkoxy-N-chloroamides with silver ions in ethereal solvents.These intermediates readily cyclise onto aromatic nuclei on alkoxy side-chains to give benzoxazines and benzoxazepines and on the acyl side-chains to give γ, δ and ε benzolactams.Spirane products are formed by ipso addition when a 4-methoxy substituent is present on the side-chain aromatic rings.The yields and regioselectivities of these reactions have been ascribed to different transition structures for cyclisation onto the acyl and alkoxy side-chains which involve respectively an exocyclic and endocyclic N-O ?-bond.Evidence for this exeptionally high ?-bond character has been obtained from MNDO calculations which predict a ?-bond order of 0.9 and a rotational barrier of 29.7 kcalmol-1