126545-09-3

Basic information

• Product Name: N-(2-methoxyphenyl)-3-phenylpropanamide
• Synonyms: N-(2-methoxyphenyl)-3-phenylpropanamide
• CAS NO: 126545-09-3
• Molecular Weight: 255.316
• Mol File: 126545-09-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(2-methoxyphenyl)-3-phenylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-methoxyphenyl)-3-phenylpropanamide(126545-09-3)
• EPA Substance Registry System: N-(2-methoxyphenyl)-3-phenylpropanamide(126545-09-3)

Safety Data

• Hazardous Substances Data: 126545-09-3(Hazardous Substances Data)

Upstream product

• 112403-88-0 O-methyl N-phenyl-3-phenylpropanohydroxamate 
• 90-04-0 2-methoxy-phenylamine 
• 501-52-0 3-Phenylpropionic acid 
• 63677-96-3 (E)-2-hydroxy-2-methyl-5-phenylpent-4-en-3-one 
• 645-45-4 hydrocinnamic acid chloride 

Relevant articles and documents

Silica gel-mediated amide bond formation: An environmentally benign method for liquid-phase synthesis and cytotoxic activities of amides

An efficient, functional group tolerable, and environmentally benign process for the synthesis of amides was developed. No activation reagents or scavengers are required in this process. Purification of desired compounds is easy, rapid, and cost-effective. This protocol provides an alternative for the combinatorial liquid-phase synthesis of amide libraries for drug discovery. By this method, a number of amides were prepared and evaluated in vitro against a panel of human tumor cell lines. Cinnamic amide IV-4 was found to be the most potent compound synthesized against four human tumor cell lines.

NITROGEN-CONTAINING HETEROARYL COMPOUNDS HAVING HIV INTEGRASE INHIBITORY ACTIVITY

A compound of the formula (I): wherein Z4, Z5 and Z9 each is independently carbon atom or nitrogen atom; Y is hydroxy, mercapto or amino; RA is a group of the formula: (wherein C ring is nitrogen-containing heteroaryl) has an inhibitory activity against integrase.