1126320-27-1

Basic information

• Product Name: 4-Chloro-2-fluoro-5-methylphenylboronic acid,pinacol
• Synonyms: 4-Chloro-2-fluoro-5-methylphenylboronic acid,pinacol;2-(4-Chloro-2-fluoro-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;4-Chloro-2-fluoro-5-methylphenylboronic acid, pinacol ester
• CAS NO: 1126320-27-1
• Molecular Formula: C₁₃H₁₇BClFO₂
• Molecular Weight: 270.5352832
• Mol File: 1126320-27-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Chloro-2-fluoro-5-methylphenylboronic acid,pinacol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-2-fluoro-5-methylphenylboronic acid,pinacol(1126320-27-1)
• EPA Substance Registry System: 4-Chloro-2-fluoro-5-methylphenylboronic acid,pinacol(1126320-27-1)

Safety Data

• Hazardous Substances Data: 1126320-27-1(Hazardous Substances Data)

Usage

Uses

4-Chloro-2-fluoro-5-methylphenylboronic acid, pinacol ester

Upstream product

• 452-73-3 2-chloro-4-fluorotoluene 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 73183-34-3 bis(pinacol)diborane 

Relevant articles and documents

A C-H borylation approach to suzuki-miyaura coupling of typically unstable 2-heteroaryl and polyfluorophenyl boronates

A method for the synthesis of biaryls and heterobiaryls from arenes and haloarenes without the intermediacy of unstable boronic acids is described. Pinacol boronate esters that are analogous to unstable boronic acids are formed in high yield by iridium-catalyzed C-H borylation of heteroarenes and fluoroarenes. These boronates are stable in the solid state or in solution and can be generated and used in situ. They couple with aryl halides in the presence of simple palladium catalysts, providing a convenient route to biaryl and heteroaryl products that have been challenging to prepare via boronic acids.

2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES

2-(Substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylic acid and its derivatives are potent herbicides demonstrating broad spectrum of weed control.