112984-60-8 Usage
Description
6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid is a complex organic compound that is a metabolite of Prulifloxacin (P838885). It belongs to the quinolone class of antibiotics and exhibits potent antimicrobial activity. This yellow solid is characterized by its unique chemical structure, which includes a fluorine atom, a methyl group, and a piperazine ring, among other features.
Uses
Used in Pharmaceutical Industry:
6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid is used as an active pharmaceutical ingredient for the development of new antibiotics. Its effectiveness against pneumonia highlights its potential in treating respiratory infections caused by bacteria.
Used in Research and Development:
As a metabolite of Prulifloxacin, this compound is also used in research and development for understanding the metabolic pathways and pharmacokinetics of quinolone antibiotics. This knowledge can contribute to the optimization of drug formulations and the development of more effective treatments.
Used in Quality Control and Analysis:
6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid can be employed as a reference compound in quality control processes and analytical methods for the detection and quantification of related compounds in pharmaceutical products and biological samples.
Chemical Properties:
The chemical properties of 6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid include its appearance as a yellow solid, which is indicative of its stability and purity. Its specific chemical structure endows it with unique reactivity and binding properties, making it a valuable compound for various applications in the pharmaceutical and chemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 112984-60-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,9,8 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 112984-60:
(8*1)+(7*1)+(6*2)+(5*9)+(4*8)+(3*4)+(2*6)+(1*0)=128
128 % 10 = 8
So 112984-60-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H16FN3O3S/c1-8-20-11-7-12(19-4-2-18-3-5-19)10(17)6-9(11)14(21)13(16(22)23)15(20)24-8/h6-8,18H,2-5H2,1H3,(H,22,23)
112984-60-8Relevant articles and documents
Ulifloxacin hydrochloride crystal as well as preparation method and application thereof
-
Paragraph 0057; 0058, (2018/03/24)
The invention provides an ulifloxacin hydrochloride crystal. The crystal uses an X-ray powder diffraction pattern of Cu-Ka radiation and has following peaks denoted with 2theta angles: 8.859 degrees plus or minus 0.2 degrees, 15.233 degrees plus or minus 0.2 degrees, 15.284 degrees plus or minus 0.2 degrees, 22.153 degrees plus or minus 0.2 degrees, 25.217 degrees plus or minus 0.2 degrees and 26.750 degrees plus or minus 0.2 degrees. The invention also provides a preparation method of the crystal, medicine composition containing the crystal as well as a pharmaceutical application of the crystal and the medicine composition. The provided crystal has good reproducibility, the preparation method is simple, and dosage of an organic solvent is reduced. Experiments prove that the novel crystal and an original ulifloxacin hydrochloride crystal both have a remarkable effect in the aspects of solubility, stability, moisture absorption and in-vivo therapy effect, and the novel crystal can be prepared in multiple dosage forms and has good clinical application potential.
A method for preparing of plurichari (by machine translation)
-
Paragraph 0024; 0037; 0038; 0039, (2016/10/07)
The invention relates to a prepration method of a compound prulifloxacin as shown in the formula (I), wherein the chemical name of prulifloxacin is 6-floro-1-methyl-7-[4-(5-methyl-2-oxo1,3-dioxo hetercyclopentene-4-yl)methyl-1-piperazinyl-4-oxo-4H-[1,3] thiaazacyclobutane[3,2-a] quinoline-3-carboxylic acid. The preparation method provided by the invention is a preparation method of prulifloxacin suitable for industrialized production, simple in process, high in purity and high in yield.
PROCESS FOR THE PREPARATION OF HIGHLY PURE PRULIFLOXACIN
-
Page/Page column 15, (2009/09/05)
The present invention provides an industrially advantageous process for the preparation of highly pure prulifloxacin of formula I and its pharmaceutically acceptable salts. The present i innvention a also provides a novel process for the purification of prulifloxacin acid addition salt.