113094-08-9Relevant articles and documents
Synthetic method of chromone derivative
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Paragraph 0078-0081, (2020/09/16)
The invention discloses a chromone derivative synthesis method, which comprises: dissolving a compound RXXR in a solvent, adding [bis(trifluoroacetoxy)iodine]benzene (short for PIFA), carrying out a reaction for 8-15 min, adding a 2-methoxyphenyl acetylen
Preparation method of 3-arylmercapto flavonoid compound
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Paragraph 0032; 0033; 0034; 0038, (2018/02/04)
The invention discloses a preparation method of a 3-arylmercapto flavonoid compound. The preparation method comprises the following steps: taking 1-(2-methoxyaryl)-3-aryl propargyl ketone as a substrate, adding N-arylthiobenzamide as a sulfur source into the substrate, adding a promoter, and in a reaction solvent, enabling reaction for 20 hours while stirring at the room temperature of 25 DEG C and under atmospheric pressure; after completion of the reaction, filtering a reaction solution to obtain a filtrate; concentrating the filtrate, removing the solvent by using a rotary evaporator to obtain a remainder, performing chromatography on the remainder by using a silica gel column, eluting by using an eluent, and collecting effluent according to an actual gradient; and combining the effluent containing the 3-arylmercapto flavonoid compound, concentrating the combined effluent to remove the solvent, and finally performing vacuum drying to obtain the target product. The preparation method has the advantages of simple preparation process, less pollution, low energy consumption and high yield.