1132829-55-0

Basic information

• Product Name: N-((R)-2,2,2-trifluoro-1-(7-ethyl-1H-indol-3-yl)ethyl)-3,4,5-trimethoxybenzenamine
• Synonyms: N-((R)-2,2,2-trifluoro-1-(7-ethyl-1H-indol-3-yl)ethyl)-3,4,5-trimethoxybenzenamine
• CAS NO: 1132829-55-0
• Molecular Weight: 408.42
• Mol File: 1132829-55-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-((R)-2,2,2-trifluoro-1-(7-ethyl-1H-indol-3-yl)ethyl)-3,4,5-trimethoxybenzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-((R)-2,2,2-trifluoro-1-(7-ethyl-1H-indol-3-yl)ethyl)-3,4,5-trimethoxybenzenamine(1132829-55-0)
• EPA Substance Registry System: N-((R)-2,2,2-trifluoro-1-(7-ethyl-1H-indol-3-yl)ethyl)-3,4,5-trimethoxybenzenamine(1132829-55-0)

Safety Data

• Hazardous Substances Data: 1132829-55-0(Hazardous Substances Data)

Upstream product

• 22867-74-9 7-ethyl-1H-indole 
• 431-46-9 2,2,2-trifluoro-1-methoxy-ethanol 
• 24313-88-0 3,4,5-Trimethoxyaniline 

Relevant articles and documents

Chiral Bronsted acid-mediated enantioselective organocatalytic three-component reaction for the construction of trifluoromethyl-containing molecules

In combination with the advantages of organocatalysis, we have developed a highly enantioselective Friedel-Crafts aminoalkylation of indoles with imines generated in situ from trifluoroacetaldehyde methyl hemiacetal and aniline. Novel chiral trifluoromethyl-containing compounds were obtained in high yields with excellent enantioselectivities. This methodology was further extended to difluoroacetaldehyde methyl hemiacetal to demonstrate the broad scope of substrates.