113372-57-9Relevant articles and documents
Triazene Drug Metabolites. Part 5. A Simple Direct Synthesis of 3-Alkoxymethyl- and 3-Alkylthiomethyl-1-aryl-3-alkyltriazenes from 1-Aryl-3-hydroxymethyl-3-alkyltriazenes.
Iley, Jim,Rosa, Eduarda,Fernandes, Leonor
, p. 2216 - 2229 (2007/10/02)
Reaction of 1-aryl-3-hydroxymethyl-3-methyltriazenes with an alcohol in the presence of hydrogen chloride under anhydrous conditions gives rise to the corresponding 1-aryl-3-alkoxymethyl-3-methyltriazenes in excellent yield.The reaction is acid catalysed and probably proceeds through a triazenyliminium ion.Alkylthio derivatives can also be formed from thiols, but the synthesis fails for both amines, and alcohols containing an amino group.