1135025-53-4

Basic information

• Product Name: 2-[5-(4-fluorophenoxy)pentyl]-3-methylquinolin-4(1H)-one
• CAS NO: 1135025-53-4
• Molecular Weight: 339.41
• Mol File: 1135025-53-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[5-(4-fluorophenoxy)pentyl]-3-methylquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[5-(4-fluorophenoxy)pentyl]-3-methylquinolin-4(1H)-one(1135025-53-4)
• EPA Substance Registry System: 2-[5-(4-fluorophenoxy)pentyl]-3-methylquinolin-4(1H)-one(1135025-53-4)

Safety Data

• Hazardous Substances Data: 1135025-53-4(Hazardous Substances Data)

Upstream product

• 1135031-28-5 [4-(4-fluorophenoxy]butyl]triphenylphosphonium bromide 
• 2033-80-9 1-bromo-4-(p-fluorophenoxy)butane 

Relevant articles and documents

QUINOLONE DERIVATIVE

As a result of extensive studies on NAD(P)H oxidase inhibitors, the present inventors found that a quinolone derivative having, at the 2-position, an alkyl group substituted with a heteroatom or the like has an excellent NAD(P)H oxidase inhibitory activity, and accomplished the present invention. The compound of the present invention has a reactive oxygen species production inhibitory activity based on the NAD(P)H oxidase inhibitory activity, and therefore can be used as an agent for preventing and/or treating diabetes, impaired glucose tolerance, hyperlipidemia, fatty liver, diabetetic complications and the like.