113566-74-8

Basic information

• Product Name: 1,2-Propanediol, 2-benzoate, (2R)-
• CAS NO: 113566-74-8
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• Mol File: 113566-74-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1,2-Propanediol, 2-benzoate, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Propanediol, 2-benzoate, (2R)-(113566-74-8)
• EPA Substance Registry System: 1,2-Propanediol, 2-benzoate, (2R)-(113566-74-8)

Safety Data

• Hazardous Substances Data: 113566-74-8(Hazardous Substances Data)

Upstream product

• 131429-78-2 C₂₂H₃₃NO₄Si 
• 871580-89-1 [(1R)-2-[tert-butyl(dimethyl)silyl]oxy-1-methyl-ethyl]benzoate 
• 19224-26-1 1,2-bis-benzoyloxy-propane 
• 98-88-4 benzoyl chloride 
• 65-85-0 benzoic acid 
• 15448-47-2 (R)-propylene oxide 
• 57-55-6 propylene glycol 
• 123-38-6 propionaldehyde 
• 94-36-0 dibenzoyl peroxide 
• 78871-04-2 (R)-1-oxopropan-2-yl benzoate 

Downstream Products

• 113534-14-8 (S)-1-(tert-butyldimethylsiloxy)-2-(benzoyloxy)propane 
• 78871-04-2 (R)-1-oxopropan-2-yl benzoate 
• 871580-90-4 (1R)-2-bromo-1-methylethyl benzoate 

Relevant articles and documents

PRODRUGS OF CHLOROKYNURENINES

The present disclosure relates to prodrugs of 7-chlorokynurenic acid. In certain embodiments, the prodrugs include those having the structure of any one of formula (I)-(VIII), wherein R1-R13, monomer 1, monomer 2, and linker are defi

Enantioselective syn and anti homocrotylation of aldehydes: Application to the formal synthesis of spongidepsin

Whereas crotylboration has been a useful method for synthesis of stereochemically complex products, we have shown that homocrotylboration can be achieved with cyclopropanated crotylation reagents, and that the stereoselectivity of the reaction can be predicted by analogous models. This paper presents a full account of this work, including the first examples of asymmetric anti homocrotylation. The scope of this reaction is demonstrated with highly enantioselective homocrotylation of both aliphatic and aromatic aldehydes, as well as double diastereoselection studies. An application of the synthesis of the marine natural product spongidepsin is presented, as well as streamlined syntheses of homocrotylation reagents.

Kinetic resolution of 1,2-diols using nitrogen-tethered bisimidazoline-copper(I) catalyzed benzoylation

Nitrogen-tethered bisimidazoline (Nb-imidazoline) ligand was utilized in the Cu(I)-catalyzed benzoylation of 1,2-diols. With the assistance of i-Pr2NEt, the reaction of rac-1,2-diols with o-methylbenzoyl chloride was smoothly catalyzed by Nb-imidazoline-CuCl in CH2Cl2 to give the corresponding o-methylbenzoylated secondary alcohols in up to 79% ee.