114460-08-1 Usage
Description
1-(4-AMINOPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-3.4-DIHYDRO-5H-2,3-BENZODIAZEPINE is a chemical compound belonging to the benzodiazepine class of drugs. It is a psychoactive substance known for its sedative, anxiolytic, and hypnotic properties. 1-(4-AMINOPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-3.4-DIHYDRO-5H-2,3-BENZODIAZEPINE is structurally related to benzodiazepines and has been investigated for its potential therapeutic use in treating anxiety, insomnia, and other central nervous system disorders. Its chemical structure, which includes an aminophenyl group, a methyl group, and a methylenedioxy group, plays a significant role in its pharmacological effects. While it may have potential medical applications, it also carries a risk of abuse and dependence, necessitating cautious use.
Uses
Used in Pharmaceutical Industry:
1-(4-AMINOPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-3.4-DIHYDRO-5H-2,3-BENZODIAZEPINE is used as a therapeutic agent for the treatment of anxiety and insomnia. Its anxiolytic and sedative properties make it a potential candidate for managing central nervous system disorders.
Used in Research and Development:
In the field of neuroscience and pharmacology, 1-(4-AMINOPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-3.4-DIHYDRO-5H-2,3-BENZODIAZEPINE is used as a research compound to study the effects of benzodiazepines on the central nervous system and to develop new medications with improved safety profiles and reduced potential for abuse.
Used in Drug Abuse Prevention and Treatment:
Due to its potential for abuse and dependence, 1-(4-AMINOPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-3.4-DIHYDRO-5H-2,3-BENZODIAZEPINE may also be utilized in the development of strategies and treatments aimed at preventing and managing substance abuse, particularly related to benzodiazepines.
Check Digit Verification of cas no
The CAS Registry Mumber 114460-08-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,4,6 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 114460-08:
(8*1)+(7*1)+(6*4)+(5*4)+(4*6)+(3*0)+(2*0)+(1*8)=91
91 % 10 = 1
So 114460-08-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H17N3O2/c1-10-6-12-7-15-16(22-9-21-15)8-14(12)17(20-19-10)11-2-4-13(18)5-3-11/h2-5,7-8,10,19H,6,9,18H2,1H3
114460-08-1Relevant articles and documents
A simple and efficient synthesis of GYKI 52466 and GYKI 52895
Zappala, Maria,Grasso, Silvana,Micale, Nicola,Polimeni, Santina,De Micheli, Carlo
, p. 527 - 533 (2007/10/03)
The synthesis of 1-(4-aminophenyl)-4-methyl-7,8-methylene-dioxy-5H-2,3-benzodiazepine (GYKI 52466, 1), the prototype of a series of noncompetitive AMPA receptor antagonists, and its 3,4-dihydroderivative (GYKI 52895, 2) is described. The title compounds have been prepared starting from safrole through a quite effective procedure.
