115127-31-6Relevant articles and documents
N-SULFONYL INDOLE DERIVATIVE COMPOUND AND USE THEREOF
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, (2016/10/07)
PROBLEM TO BE SOLVED: To provide an N-sulfonyl indole derivative compound useful for the treatment of cancer and hypertension. SOLUTION: This invention provides an N-sulfonyl indole derivative compound represented by formula (1) where R1 is an aryl group, cycloalkyl group or heteroaryl group, and R2 is Si(R5)(R6)(R7), C1-C6 alkyl group or acetyl group. COPYRIGHT: (C)2016,JPOandINPIT
SYNTHESIS AND REACTIVITY OF 2-(1',3'-DITHIAN-2'-YL)INDOLES
Rubiralta, Mario,Casamitjana, Nuria,Grierson, David S.,Husson, Henri-Philippe
, p. 443 - 450 (2007/10/02)
The 2-(1',3'-dithian-2'-yl)indoles 1a,b were prepared in a single operation involving reaction of anions of the N-protected indoles 3a,b with 2-chloro-1,3-dithiane.Subsequent reaction of 1a with excess n-BuLi followed by an electophile (1-methyl-4-piperid