115413-92-8Relevant articles and documents
Desulfurizative titanation of allyl sulfides. Regio and diastereoselective preparation of homoallyl alcohols
Takeda, Takeshi,Miura, Ichiro,Horikawa, Yasuo,Fujiwara, Tooru
, p. 1495 - 1498 (1995)
The successive treatments of allyl sulfides with the low-valent organotitanium species, prepared by the reaction of tianocene dichloride with 2 equiv. of butyllithium, and aldehydes gave the homoallyl alcohols with high regio and diastereoselectivity in good yields.
Generation of allylic titanocene derivatives from vinyl halides and a Cp2TiCl2-Me3Al reagent system
Hanzawa, Yuji,Kowase, Noboru,Taguchi, Takeo
, p. 583 - 586 (1998)
The reagent prepared in advance by stirring a mixture of a Cp2TiCl2-Me3Al reagent system in the ratio of 1 : 4 in toluene for 3 days is found to be effective in generating allylic titanocene on treatment with vinyl halides in THF.
Chelation versus Non-Chelation Control in the Stereoselective Alkenyl sp2 C?H Bond Functionalization Reaction
Liang, Qiu-Ju,Yang, Chao,Meng, Fei-Fan,Jiang, Bing,Xu, Yun-He,Loh, Teck-Peng
supporting information, p. 5091 - 5095 (2017/04/24)
A hydroxy group chelation-assisted stereospecific oxidative cross-coupling reaction between alkenes was developed under mild reaction conditions. In the presence of palladium catalyst, the alkenes tethered with hydroxy functionality can couple efficiently with electron-deficient alkenes to form the corresponding multi-substituted olefin products. The hydroxy group on the substrate could play dual roles in reaction, acting as the directing group for alkenyl C?H bond activation and controlling the stereoselectivity of the products.
Hydroxyl-directed stereoselective diboration of alkenes
Blaisdell, Thomas P.,Caya, Thomas C.,Zhang, Liang,Sanz-Marco, Amparo,Morken, James P.
supporting information, p. 9264 - 9267 (2014/07/21)
An alkoxide-catalyzed directed diboration of alkenyl alcohols is described. This reaction occurs in a stereoselective fashion and is demonstrated with cyclic and acyclic homoallylic and bishomoallylic alcohol substrates. After oxidation, the reaction generates 1,2-diols such that the process represents a method for the stereoselective directed dihydroxylation of alkenes.