115833-91-5

Basic information

• Product Name: 1-(4-(4-morpholinylphenyl))ethan-1-ol
• Synonyms: 1-(4-(4-morpholinylphenyl))ethan-1-ol
• CAS NO: 115833-91-5
• Molecular Weight: 207.272
• Mol File: 115833-91-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1-(4-(4-morpholinylphenyl))ethan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(4-morpholinylphenyl))ethan-1-ol(115833-91-5)
• EPA Substance Registry System: 1-(4-(4-morpholinylphenyl))ethan-1-ol(115833-91-5)

Safety Data

• Hazardous Substances Data: 115833-91-5(Hazardous Substances Data)

Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 
• 39910-98-0 4-morpholinoacetophenone 

Downstream Products

• 1344921-45-4 (S)-1-[4-(morpholin-4-yl)phenyl]ethanol 
• 2524-67-6 4-morpholino-4-yl-phenylamine 
• 1019780-37-0 C₁₅H₁₉N₃O 

Relevant articles and documents

Selective Carbon-Carbon Bond Amination with Redox-Active Aminating Reagents: A Direct Approach to Anilines?

Amines are among the most fundamental motifs in chemical synthesis, and the introduction of amine building blocks via selective C—C bond cleavage allows the construction of nitrogen compounds from simple hydrocarbons through direct skeleton modification. Herein, we report a novel method for the preparation of anilines from alkylarenes via Schmidt-type rearrangement using redox-active amination reagents, which are easily prepared from hydroxylamine. Primary amines and secondary amines were prepared from corresponding alkylarenes or benzyl alcohols under mild conditions. Good compatibility and valuable applications of the transformation were also displayed.

Silver-Catalyzed Hydrogenation of Ketones under Mild Conditions

The silver-catalyzed hydrogenation of ketones using H2 as hydrogen source is reported. Silver nanoparticles are generated from simple silver (I) salts and operate at 25 °C under 20 bar of hydrogen pressure. Various aliphatic and aromatic ketones, including natural products were reduced into the corresponding alcohols in high yields. This silver catalyst allows for the selective hydrogenation of ketones in the presence of other functional groups. (Figure presented.).

Hydrogenation of Carbonyl Derivatives with a Well-Defined Rhenium Precatalyst

The first efficient and general rhenium-catalyzed hydrogenation of carbonyl derivatives was developed. The key to the success of the reaction was the use of a well-defined rhenium complex bearing a tridentate diphosphinoamino ligand as the catalyst (0.5 mol %) at 70 °C in the presence of H2 (30 bar). The mechanism of the reaction was investigated by DFT(PBE0-D3) calculations.