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2524-67-6

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2524-67-6 Usage

Uses

Different sources of media describe the Uses of 2524-67-6 differently. You can refer to the following data:
1. 4-Morpholinoaniline is a morpholine derivative used in the preparation of central nervous system (CNS) active agents. 4-Morpholinoaniline is also one of the primary aromatic amines used in the colour developing process in photographs.
2. 4-(4-Morpholinyl)aniline is used in the preparation of central nervous system (CNS) active agents, also used in the color developing process in photographs.

Check Digit Verification of cas no

The CAS Registry Mumber 2524-67-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,2 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2524-67:
(6*2)+(5*5)+(4*2)+(3*4)+(2*6)+(1*7)=76
76 % 10 = 6
So 2524-67-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O/c11-9-1-3-10(4-2-9)12-5-7-13-8-6-12/h1-4H,5-8,11H2

2524-67-6 Well-known Company Product Price

  • Brand
  • (Code)Product description
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  • Packaging
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  • Alfa Aesar

  • (B20292)  4-(4-Morpholinyl)aniline, 98+%   

  • 2524-67-6

  • 2.5g

  • 331.0CNY

  • Detail
  • Alfa Aesar

  • (B20292)  4-(4-Morpholinyl)aniline, 98+%   

  • 2524-67-6

  • 5g

  • 598.0CNY

  • Detail
  • Alfa Aesar

  • (B20292)  4-(4-Morpholinyl)aniline, 98+%   

  • 2524-67-6

  • 25g

  • 2390.0CNY

  • Detail
  • Alfa Aesar

  • (B20292)  4-(4-Morpholinyl)aniline, 98+%   

  • 2524-67-6

  • 50g

  • 4300.0CNY

  • Detail
  • Aldrich

  • (197157)  4-Morpholinoaniline  ≥98%

  • 2524-67-6

  • 197157-5G

  • 802.62CNY

  • Detail

2524-67-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-morpholin-4-ylaniline

1.2 Other means of identification

Product number -
Other names 4-Morpholinyl aniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2524-67-6 SDS

2524-67-6Relevant articles and documents

Method for preparing amine through catalytic reduction of nitro compound by cyclic (alkyl) (amino) carbene chromium complex

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Paragraph 0015, (2021/04/17)

The cyclic (alkyl) (amino) carbene chromium complex is prepared from corresponding ligand salt, alkali and CrCl3 and used for catalyzing pinacol borane to reduce nitro compounds in an ether solvent under mild conditions to generate corresponding amine. The method for preparing amine has the advantages of cheap and accessible raw materials, mild reaction conditions, wide substrate application range, high selectivity and the like, and is simple to operate.

2, 6, 8 - Polysubstituted imidazo [1, 2 - a] pyrazine and synthesis method and application thereof

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Paragraph 0029; 0032; 0036-0038, (2021/10/11)

The invention discloses I, 2 and 6 polysubstituted imidazo [8 - 1] pyrazine of formula (2 - a) or a pharmaceutically acceptable salt thereof. The invention also discloses application of the 2, 6 and 8 - polysubstituted imidazo [1, 2 - a] pyrazine or pharmaceutically acceptable salts thereof as TYK2 inhibitors in preparation of drugs for preventing and treating tumor or inflammation diseases. The invention also provides a synthetic method of the 2, 6, 8 - polysubstituted imidazo [1, 2 - a] pyrazine or a pharmaceutically acceptable salt thereof.

Optimization of WZ4003 as NUAK inhibitors against human colorectal cancer

Yang, Huali,Wang, Xiaobing,Wang, Cheng,Yin, Fucheng,Qu, Lailiang,Shi, Cunjian,Zhao, Jinhua,Li, Shang,Ji, Limei,Peng, Wan,Luo, Heng,Cheng, Maosheng,Kong, Lingyi

, (2020/12/15)

NUAK, the member of AMPK (AMP-activated protein kinase) family of protein kinases, is phosphorylated and activated by the LKB1 (liver kinase B1) tumor suppressor protein kinase. Recent work has indicated that NUAK1 is a key component of the antioxidant stress response pathway, and the inhibition of NUAK1 will suppress the growth and survival of colorectal tumors. As a promising target for anticancer drugs, few inhibitors of NUAK were developed. With this goal in mind, based on NUAK inhibitor WZ4003, a series of derivatives has been synthesized and evaluated for anticancer activity. Compound 9q, a derivative of WZ4003 by removing a methoxy group, was found to be the most potential one with stronger inhibitory against NUAK1/2 enzyme activity, tumor cell proliferation and inducing apoptosis of tumor cells. By in vivo efficacy evaluations of colorectal SW480 xenografts, 9q suppresses tumor growth more effectively with an excellent safety profile in vivo and is therefore seen as a suitable candidate for further investigation.

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