115891-03-7

Basic information

• Product Name: 2-(3,4,5-Trimethoxy-phenylamino)-nicotinic acid
• Synonyms: 2-(3,4,5-Trimethoxy-phenylamino)-nicotinic acid
• CAS NO: 115891-03-7
• Molecular Formula: C₁₅H₁₆N₂O₅
• Molecular Weight: 304
• Mol File: 115891-03-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3,4,5-Trimethoxy-phenylamino)-nicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4,5-Trimethoxy-phenylamino)-nicotinic acid(115891-03-7)
• EPA Substance Registry System: 2-(3,4,5-Trimethoxy-phenylamino)-nicotinic acid(115891-03-7)

Safety Data

• Hazardous Substances Data: 115891-03-7(Hazardous Substances Data)

Upstream product

• 2942-59-8 2-chloronicotinic acid 
• 1373554-61-0 ethyl 2-((3,4,5-trimethoxyphenyl)amino)nicotinate 
• 24313-88-0 3,4,5-Trimethoxyaniline 
• 1452-94-4 ethyl 2-chloronicotinate 

Downstream Products

• 1393658-14-4 N-3-(6-fluoro-1,3-benzothiazol-2-yl)-2-(3,4,5-trimethoxyanilino)nicotinamide 
• 1393658-15-5 N₃-(6-methoxy-1,3-benzothiazol-2-yl)-2-(3,4,5-trimethoxyanilino)nicotinamide 
• 115891-87-7 3-Butyl-4-hydroxy-1-(3,4,5-trimethoxy-phenyl)-1H-[1,8]naphthyridin-2-one 
• 115891-20-8 2-(3,4,5-Trimethoxy-phenylamino)-nicotinic acid methyl ester 

Relevant articles and documents

Synthesis and mechanistic aspects of 2-anilinonicotinyl-pyrazolo[1,5-a]pyrimidine conjugates that regulate cell proliferation in MCF-7 cells via estrogen signaling

A series of anilinonicotinyl linked pyrazolo[1,5-a]pyrimidine conjugates (6a-x) were synthesized and evaluated for their antiproliferative activity. Some of these conjugates exhibited promising cytotoxic effects in the MCF-7 cell line and among these 6a a

Synthesis of 2-anilinopyridine dimers as microtubule targeting and apoptosis inducing agents

A series of 2-anilinopyridine dimers have been synthesized and evaluated for their anticancer potential. Most of the compounds have showed significant growth inhibition of the cell lines tested and compound 4d was most effective amongst the series display

2-ANILINO NICOTINYL LINKED 2-AMINO BENZOTHIAZOLE CONJUGATES AND PROCESS FOR THE PREPARATION THEREOF

The present invention provides compounds of general formula A useful as potential anticancer agents against human cancer cell lines and apoptosis inducers. The present invention further provides a process for the preparation of 2-anilino nicotinyl linked 2-amino benzothiazole conjugates of general formula (A), wherein R1 = H or CI; R2 = H, OCH3 or F; R3 = H, OCH3, F or CI; R4=H, OCH3 or F and X= OCH3, F or N02.