1160359-85-2Relevant articles and documents
Discovery of a potent pyrazolopyridine series of γ-secretase modulators
Qin, Jun,Zhou, Wei,Huang, Xianhai,Dhondi, Pawan,Palani, Anandan,Aslanian, Robert,Zhu, Zhaoning,Greenlee, William,Cohen-Williams, Mary,Jones, Nicholas,Hyde, Lynn,Zhang, Lili
, p. 471 - 476 (2011/08/22)
The synthesis and structure-activity relationship of a novel series of pyrazolopyridines are reported. These compounds represent a new class of γ-secretase modulators that demonstrate good in vitro potency in inhibiting Aβ42 production. Example