1160823-30-2

Basic information

• Product Name: N-(2-chlorophenyl)[1,1′-biphenyl]-4-amine
• Synonyms: N-(2-chlorophenyl)[1,1′-biphenyl]-4-amine
• CAS NO: 1160823-30-2
• Molecular Weight: 279.769
• Mol File: 1160823-30-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2-chlorophenyl)[1,1′-biphenyl]-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chlorophenyl)[1,1′-biphenyl]-4-amine(1160823-30-2)
• EPA Substance Registry System: N-(2-chlorophenyl)[1,1′-biphenyl]-4-amine(1160823-30-2)

Safety Data

• Hazardous Substances Data: 1160823-30-2(Hazardous Substances Data)

Upstream product

• 1591-31-7 4-iodo-biphenyl 
• 95-51-2 o-chloroaniline 
• 533-17-5 N-(2-chlorophenyl)acetamide 

Downstream Products

• 103012-26-6 3-phenyl-9H-carbazole 

Relevant articles and documents

Direct para-Selective C-H Amination of Iodobenzenes: Highly Efficient Approach for the Synthesis of Diarylamines

Iodine(III)-mediated synthesis of 4-iodo-N-phenylaniline from iodobenzene has been achieved, and the reaction can proceed under mild conditions. A variety of functional groups were well tolerated, providing the corresponding products in moderate to good yields. The remaining iodine group provides an effective platform for converting the products into several valuable asymmetric diphenylamines. Most importantly, this reaction can be easily scaled up to the ten-gram scale, highlighting its synthetic utility. The mechanistic study revealed that the in situ generated aryl hypervalent iodine intermediate is the key factor to realize this para-selective C-H amination reaction.