116218-80-5

Basic information

• Product Name: Ethanone, 1-[3-methoxy-4-(2-propenyloxy)phenyl]-
• CAS NO: 116218-80-5
• Molecular Formula: C12H14O3
• Molecular Weight: 206.241
• Mol File: 116218-80-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[3-methoxy-4-(2-propenyloxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[3-methoxy-4-(2-propenyloxy)phenyl]-(116218-80-5)
• EPA Substance Registry System: Ethanone, 1-[3-methoxy-4-(2-propenyloxy)phenyl]-(116218-80-5)

Safety Data

• Hazardous Substances Data: 116218-80-5(Hazardous Substances Data)

Upstream product

• 106-95-6 allyl bromide 
• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 

Relevant articles and documents

Traceless Photolabile Linker Expedites the Chemical Synthesis of Complex Oligosaccharides by Automated Glycan Assembly

Automated glycan assembly (AGA) aims at accelerating access to synthetic oligosaccharides to meet the demand for defined glycans as tools for molecular glycobiology. The linkers used to connect the growing glycan chain to the solid support play a pivotal

Synthesis and biological evaluation of 3-alkyl-1,5-diaryl-1H-pyrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative activity

A series of novel 3-alkyl-1,5-diaryl-1H-pyrazoles were synthesized as combretastatin A-4 (CA-4) analogues and evaluated for antiproliferative activity against three human cancer cell lines (SGC-7901, A549 and HT-1080). Most of the target compounds displayed moderate to potent antiproliferative activity, and 7k was found to be the most potent compound. Structure-activity relationships indicated that compounds with a trimethoxyphenyl A-ring at the N-1 position of the pyrazole skeleton were more potent than those with the A-ring at the C-5 position. Tubulin polymerization and immunostaining experiments revealed that 7k potently inhibited tubulin polymerization and disrupted tubulin microtubule dynamics in a manner similar to CA-4. Computational modelling demonstrated that the binding of 7k to the colchicine binding site on microtubules may involve a similar mode as CA-4.

4,4-dimethyl-1-phenylpentane-1,3-dione derivative and UV ray absorbent and cosmetic containing the same

A 4,4-Dimethyl-1-phenylpentane-1,3-dione derivatives represented by the following formula (1): STR1 wherein all symbols are defined in the disclosure, is disclosed. An ultraviolet ray absorbent and a cosmetic comprising the derivative are also disclosed.