117049-08-8

Basic information

• Product Name: (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl<(tert-butoxycarbonyl)amino>bromoacetate
• CAS NO: 117049-08-8
• Molecular Weight: 468.431
• Mol File: 117049-08-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl<(tert-butoxycarbonyl)amino>bromoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl<(tert-butoxycarbonyl)amino>bromoacetate(117049-08-8)
• EPA Substance Registry System: (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl<(tert-butoxycarbonyl)amino>bromoacetate(117049-08-8)

Safety Data

• Hazardous Substances Data: 117049-08-8(Hazardous Substances Data)

Upstream product

• 117681-86-4 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (tert-butoxycarbonyl)aminoacetate 
• 65253-04-5 (-)-8-phenylmenthol 
• 4530-20-5 BOC-glycine 

Downstream Products

• 117049-13-5 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (S)-2-<(tert-butoxycarbonyl)amino>-2-phenylacetate 
• 145280-12-2 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl<(tert-butoxycarbonyl)imino>acetate 
• 38329-34-9 (S)-α-amino-α-phenylacetic acid hydrochloride 
• 25705-52-6 (R)-phenylglycine hydrochloride 
• 1004759-86-7 (S)-N-Boc-(2-methylphenyl)glycine (-)-8-phenylmenthol ester 
• 2900-27-8 2-(tert-butoxycarbonylamino)-2-phenylacetic acid 
• 102089-74-7 tert-butyl 2-hydroxy-1-phenylethylcarbamate 
• 142121-48-0 tert-butyl (1-hydroxy-4-methylpentan-2-yl)carbamate 
• 169556-48-3 rac-tert-butyl (1-hydroxy-3-methylbutan-2-yl)carbamate 
• 147252-84-4 tert-butyl (1-hydroxypropan-2-yl)carbamate 
• 13139-15-6 Boc-DL-Leu-OH 
• 13734-41-3 N-Boc-(S/R)-valine 
• 3744-87-4 N-t-butyloxycarbonyl-DL-alanine 
• 145280-03-1 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (R)-2-<(tert-butoxycarbonyl)amino>butanoate 

Relevant articles and documents

A STEREOSELECTIVE SYNTHESIS OF N-BOC-α-AMINO ALCOHOLS AND α-AMINO ACIDS

A sterteoselective synthesis of N-Boc-α-amino alcohols and α-amino acids via the addition of Grignard reagents to the chiral electrophilic glycine equivalent α-bromo-N-Boc-glycine(-)phenylmenthylester is described.

Asymmetric Sommelet-Hauser rearrangement of N-benzylic ammonium salts

(Chemical Equation Presented) [2,3] over [1,2]: The asymmetric Sommelet-Hauser rearrangement of an ammonium salt derived from N-benzylic proline-derived or N-benzylic glycine (-)-8-phenylmenthol ester is shown to proceed with remarkably high levels of stereoselectivity. The method provides unique and efficient access to optically active α-aryl amino acid derivatives.