169556-48-3

Basic information

• Product Name: N-BOC-D/L-VALINOL
• Synonyms: N-BOC-D/L-VALINOL;Carbamic acid, [1-(hydroxymethyl)-2-methylpropyl]-, 1,1-dimethylethyl ester;tert-Butyl (1-hydroxy-3-Methylbutan-2-yl)carbaMate;Boc-DL-Valinol;1-Boc-D/L-Valinol;tert-Butyl (1-hydroxy-3-methylbutan-2-yl)
• CAS NO: 169556-48-3
• Molecular Formula: C₁₀H₂₁NO₃
• Molecular Weight: 203.28
• Product Categories: N-BOC
• Mol File: 169556-48-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-BOC-D/L-VALINOL(CAS DataBase Reference)
• NIST Chemistry Reference: N-BOC-D/L-VALINOL(169556-48-3)
• EPA Substance Registry System: N-BOC-D/L-VALINOL(169556-48-3)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 169556-48-3(Hazardous Substances Data)

Usage

Description

N-BOC-D/L-VALINOL is a chemical compound that belongs to the class of BOC-protected amino alcohols. It is characterized by a tert-butyloxycarbonyl (BOC) protecting group attached to the nitrogen atom of the valinol molecule. Valinol is a derivative of valine, a nonpolar, neutral amino acid commonly found in proteins. The BOC protecting group is often used in organic synthesis to temporarily shield the reactivity of functional groups and can be removed under mild conditions when desired. N-BOC-D/L-VALINOL has potential applications in the pharmaceutical industry as a building block for the synthesis of various drug compounds. Its versatile reactivity and ability to modify the structure of a molecule make it a valuable tool in chemical synthesis.
Used in Pharmaceutical Industry:
N-BOC-D/L-VALINOL is used as a building block for the synthesis of various drug compounds. Its versatile reactivity and ability to modify the structure of a molecule make it a valuable tool in chemical synthesis.

Upstream product

• 13734-41-3 N-Boc-(S/R)-valine 
• 516-06-3 D,L-valine 
• 16369-05-4 valinol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 117049-08-8 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl<(tert-butoxycarbonyl)amino>bromoacetate 
• 117681-86-4 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (tert-butoxycarbonyl)aminoacetate 
• 4530-20-5 BOC-glycine 
• 117049-11-3 2-tert-Butoxycarbonylamino-3-methyl-butyric acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 13734-41-3 t-Boc-L-valine 
• 530-62-1 1,1'-carbonyldiimidazole 
• 72-18-4 L-valine 

Downstream Products

• 871235-24-4 2-methyl-2-propanyl (1-amino-3-methyl-2-butanyl)carbamate 
• 1435915-78-8 C₂₅H₂₉N₃O₆S 
• 1435915-21-1 C₂₅H₂₇N₃O₆S 
• 123285-52-9 2-(S)-[N-(tert-butoxycarbonyl)amino]-3-methylbutanal 
• 317384-99-9 (+/-)-1,1-dimethylethyl [1-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-2-methylpropyl]carbamate 
• 17016-83-0 4-isopropyloxazolidin-2-one 
• 13734-41-3 N-Boc-(S/R)-valine 

Relevant articles and documents

Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues

Four mexiletine analogues have been tested for their antiarrhythmic, inotropic, and chronotropic effects on isolated Guinea pig heart tissues and to assess calcium antagonist activity, in comparison with the parent compound mexiletine. All analogues showed from moderate to high antiarrhythmic activity. In particular, three of them (1b,c,e) were more active and potent than the reference drug, while exhibiting only modest or no negative inotropic and chronotropic effects and vasorelaxant activity, thus showing high selectivity of action. All compounds showed no cytotoxicity and 1b,c,d did not impair motor coordination. All in, these new analogues exhibit an interesting cardiovascular profile and deserve further investigation.

CYANOGUANIDINES AND THEIR USE AS ANTIVIRAL AGENTS

This disclosure relates to: (a) compounds and salts thereof that, inter alia, inhibit RSV infection and/or replication; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.

An Air/water-stable tridentate N-heterocyclic carbene-palladium(II) Complex: Catalytic C-H activation of hydrocarbons via hydrogen/deuterium exchange process in deuterium oxide

While developing novel catalysts for carbon-carbon or carbon-heteroatom coupling (nitrogen, oxygen, or fluorine), we were able to introduce tridentate N-heterocyclic carbene (NHC)-amidate-alkoxide palladium(II) complexes. In aqueous solution, these NHC-Pd(II) complexes showed high ability for C-H activation of various hydrocarbons (cyclohexane, cyclopentane, dimethyl ether, tetrahydrofuran, acetone, and toluene) under mild conditions.