117067-48-8

Basic information

• Product Name: N-(1 H-BENZOTRIAZOL-1-YLPHENYLMETHYL)BENZAMIDE
• Synonyms: N-(1 H-BENZOTRIAZOL-1-YLPHENYLMETHYL)BENZAMIDE
• CAS NO: 117067-48-8
• Molecular Formula: C₂₀H₁₆N₄O
• Molecular Weight: 328.37
• Mol File: 117067-48-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 155-164 °C(lit.)
• Appearance: /
• CAS DataBase Reference: N-(1 H-BENZOTRIAZOL-1-YLPHENYLMETHYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1 H-BENZOTRIAZOL-1-YLPHENYLMETHYL)BENZAMIDE(117067-48-8)
• EPA Substance Registry System: N-(1 H-BENZOTRIAZOL-1-YLPHENYLMETHYL)BENZAMIDE(117067-48-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 117067-48-8(Hazardous Substances Data)

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 55-21-0 benzamide 
• 100-52-7 benzaldehyde 
• 117067-50-2 N-(1-Benzotriazol-1-yl-nonyl)-benzamide 

Downstream Products

• 130564-44-2 N-(2-nitro-1-phenylpropyl)benzamide 
• 134004-86-7 2-(Benzoylamino-phenyl-methyl)-2-ethyl-malonic acid diethyl ester 
• 142232-51-7 6-Butyl-2,4-diphenyl-4H-[1,3]oxazine 
• 91875-49-9 N-(1,3-diphenyl-3-oxo-propyl)-benzamide 
• 94165-04-5 ethyl 3-benzamido-3-phenylpropanoate 
• 1080529-62-9 N-[(5-bromo-1H-indol-3-yl)(phenyl)methyl]benzamide 
• 126200-32-6 ethyl 2-((1H-benzo[d][1,2,3]triazol-1-yl)(phenyl)methyl)-3-oxobutanoate 
• 1190303-60-6 methyl 2-((1H-benzo[d][1,2,3]triazol-1-yl)(phenyl)methyl)-3-oxobutanoate 
• 126200-30-4 diethyl 2-((1H-benzo[d][1,2,3]triazol-1-yl)(phenyl)methyl)malonate 
• 622851-09-6 (1S,2S)-[2-phenyl-2-benzylamino-1-(3-furyl)-ethyl]acetate 
• 745076-37-3 (2R,3S)-N-benzoyl-O-acetyl-3-phenylisoserine 
• 622851-12-1 (1S,2S)-N-[1-phenyl-2-hydroxy-2-(3-furyl)-ethyl]benzamide 
• 622851-08-5 (4S,5S)-1,4-diphenyl-5-(3-furyl)-4,5-dihydro-oxazole 
• 51608-62-9 (E)-N-benzylidenebenzamide 

Relevant articles and documents

Diastereoselective One-Pot Synthesis of Oxazolines Using Sulfur Ylides and Acyl Imines

This work describes an extended version of the Corey-Chaykovsky reaction to access oxazolines using sulfur ylides and stable precursors of acyl imines. The reaction proceeds through a mixture of aziridines and oxazolines, which provides the trans-oxazolines following in situ Heine-type aziridine ring expansion upon treatment with BF3·OEt2. Following the same one-pot procedure, amidine imides react with the sulfur ylides to provide imidazolines.

Synthesis of 3-indolylarylmethanamides by samarium triiodide catalyzed Friedel-Crafts amidoalkylation

The amidoalkylation of indoles with N-(α-benzotriazol-1-ylalkyl) amides was smoothly realized with samarium triiodide as a catalyst to give a series of novel 3-indolyl arylmethanamides with good yields and selectivities. Georg Thieme Verlag Stuttgart.

Asymmetric Sulfur Ylide Mediated Aziridination: Application in the Synthesis of the Side Chain of Taxol

(Formula presented). Sulfur ylide methodology has been used to construct the Taxol side chain with a high degree of enantioselectivity via a trans-aziridine followed by stereospecific rearrangement of the trans-benzoylaziridine into a trans-oxazoline.