745076-37-3

Basic information

• Product Name: (2R,3S)-N-benzoyl-O-acetyl-3-phenylisoserine
• Synonyms: (2R,3S)-N-benzoyl-O-acetyl-3-phenylisoserine
• CAS NO: 745076-37-3
• Molecular Weight: 327.337
• Mol File: 745076-37-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2R,3S)-N-benzoyl-O-acetyl-3-phenylisoserine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-N-benzoyl-O-acetyl-3-phenylisoserine(745076-37-3)
• EPA Substance Registry System: (2R,3S)-N-benzoyl-O-acetyl-3-phenylisoserine(745076-37-3)

Safety Data

• Hazardous Substances Data: 745076-37-3(Hazardous Substances Data)

Upstream product

• 55-21-0 benzamide 
• 98-88-4 benzoyl chloride 
• 108-24-7 acetic anhydride 
• 132201-33-3 (2R,3S)-N-benzoyl-3-phenylisoserine 
• 622851-12-1 (1S,2S)-N-[1-phenyl-2-hydroxy-2-(3-furyl)-ethyl]benzamide 
• 622851-14-3 (2S,3S)-2-(3-furyl)-3-phenyl-1-benzoylaziridine 
• 622851-08-5 (4S,5S)-1,4-diphenyl-5-(3-furyl)-4,5-dihydro-oxazole 
• 622851-11-0 (2S,3S)-2-(3-furyl)-3-phenylaziridine 
• 51608-62-9 (E)-N-benzylidenebenzamide 
• 100-52-7 benzaldehyde 
• 117067-48-8 1-benzotriazolyl-N-benzoyl-1-phenylmethylamine 
• 10387-93-6 N-(methoxy(phenyl)methyl)benzamide 
• 701305-71-7 Acetic acid (1R,2S)-2-amino-1-hydroxymethyl-2-phenyl-ethyl ester 
• 680982-37-0 (2R,3S)-2-Acetoxy-3-amino-3-phenyl-propionic acid 

Downstream Products

• 32981-85-4 methyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate 
• 1435474-96-6 (2R,3S)-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] 2-acetoxy-3-benzamido-3-phenylpropanoate 
• 1435474-97-7 (2R,3S)-[2-(7-chloroquinolin-4-ylamino)ethyl] 2-acetoxy-3-benzamido-3-phenylpropanoate 
• 1435474-99-9 (2R,3S)-[3-(7-chloroquinolin-4-ylamino)propyl] 2-acetoxy-3-benzamido-3-phenylpropanoate 
• 132201-33-3 (2R,3S)-N-benzoyl-3-phenylisoserine 
• 146848-86-4 methyl (2R,3S)-2-acetoxy-3-phenyl-3-benzoylaminopropanoate 

Relevant articles and documents

Design, synthesis, and antiplasmodial activity of hybrid compounds based on (2 R,3 S)- N-benzoyl-3-phenylisoserine

A series of hybrid compounds based on (2R,3S)-N-benzoyl-3-phenylisoserine, artemisinin, and quinoline moieties was synthesized and tested for in vitro antiplasmodial activity against erythrocytic stages of K1 and W2 strains of Plasmodium falciparum. Two hybrid compounds incorporating (2R,3S)-N-benzoyl-3- phenylisoserine and artemisinin scaffolds were 3- to 4-fold more active than dihydroartemisinin, with nanomolar IC50 values against Plasmodium falciparum K1 strain.

A highly efficient synthesis of the C-13 side-chain of taxol using Shibasaki's asymmetric Henry reaction

The synthesis of the C-13 side-chain of taxol has been achieved using Shibasaki's asymmetric Henry reaction catalyzed by an optically active rare earth lanthanum-(R)-binaphthol complex.