117296-15-8

Basic information

• Product Name: (2-(methyl(phenyl)amino)phenyl)methanol
• Synonyms: (2-(methyl(phenyl)amino)phenyl)methanol
• CAS NO: 117296-15-8
• Molecular Weight: 213.279
• Mol File: 117296-15-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2-(methyl(phenyl)amino)phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-(methyl(phenyl)amino)phenyl)methanol(117296-15-8)
• EPA Substance Registry System: (2-(methyl(phenyl)amino)phenyl)methanol(117296-15-8)

Safety Data

• Hazardous Substances Data: 117296-15-8(Hazardous Substances Data)

Upstream product

• 121-69-7 N,N-dimethyl-aniline 
• 73323-82-7 2-(N-Methyl-N-phenylamino)-benzoic acid 
• 118-91-2 ortho-chlorobenzoic acid 
• 100-61-8 N-methylaniline 
• 169170-03-0 N-methyl-N-phenylanthranilic acid methyl ester 
• 88-67-5 2-Iodobenzoic acid 
• 91-40-7 2-(phenylamino)benzoic acid 
• 62-53-3 aniline 

Downstream Products

• 719-54-0 10-methyl-9, 10-dihydro-9-acridinone 
• 30713-65-6 9-hydroxy-9,10-dihydro-10-methylacridine 
• 209412-73-7 [1-[2-(Methyl-phenyl-amino)-phenyl]-meth-(E)-ylideneaminooxy]-ethaneperoxoic acid tert-butyl ester 
• 209412-61-3 [1-[2-(Methyl-phenyl-amino)-phenyl]-meth-(E)-ylideneaminooxy]-acetic acid 
• 209412-43-1 [2-(methylanilino)phenyl](phenyl)methanone 
• 209412-50-0 2-(Methyl-phenyl-amino)-benzaldehyde oxime 
• 1859-76-3 2-(methylamino)benzophenone 
• 82772-34-7 [2-(methylanilino)phenyl](phenyl)methanole 
• 602-56-2 9-phenylacridine 
• 260-94-6 acridine 
• 208664-53-3 2-((N-methyl-N-phenyl)amino)benzaldehyde 

Relevant articles and documents

Substrate-Controlled Selectivity Switch in the Three-Component Coupling Involving Arynes, Aromatic Tertiary Amines, and CO2

The transition-metal-free multicomponent coupling involving arynes, aromatic tertiary amines, and CO2 is reported. The reaction exhibits switchable selectivity depending on the electronic nature of the aromatic amines used. With amines bearing electron-releasing/neutral groups as the nucleophilic trigger, the reaction afforded 2-arylamino benzoates via a nitrogen to oxygen alkyl group migration. Employing electron-deficient amines in the reaction furnished 2-aminoaryl benzoates proceeding via the aryl to aryl amino group migration resembling a Smiles rearrangement.

Sc(OTf)3-catalyzed dehydrogenative cyclization for synthesis of N-methylacridones

A novel method has been developed for the synthesis of substituted N-methylacridones from 2-(N-methyl-N-phenylamino)benzaldehydes via dehydrogenative cyclization. This transformation involves two primary processes: the aldehyde first coordinates with Sc(OTf)3 and induces the aromatic electrophilic substitution (SEAr) reaction to form the active intermediate N-methyl-acridin-9-ol, which is then quickly oxidized in situ to afford the acridones. Furthermore, the procedure involved is both environmental friendly and atom efficient; H2O is the only byproduct in this reaction.

Pyridyl-substituted imidazoles, compositions containing same and methods of use thereof

Novel imidazole of the formula: STR1 wherein Ring A is pyridyl group or a substituted pyridyl group; Ring B is phenyl group or a substituted phenyl group; R1 and R2 are hydrogen atom or are combined together to form a group of the formula: --(CH2)q --; m is 1 or 2; n is 0, 1 or 2; and q is 3 or 4, or a salt thereof are disclosed. Said derivative (I) and a salt thereof are useful as anti-ulcer agents.