117378-85-5

Basic information

• Product Name: Methanone, (4-methylphenyl)-1H-pyrrol-3-yl-
• CAS NO: 117378-85-5
• Molecular Formula: C12H11NO
• Molecular Weight: 185.225
• Mol File: 117378-85-5.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Methanone, (4-methylphenyl)-1H-pyrrol-3-yl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-methylphenyl)-1H-pyrrol-3-yl-(117378-85-5)
• EPA Substance Registry System: Methanone, (4-methylphenyl)-1H-pyrrol-3-yl-(117378-85-5)

Safety Data

• Hazardous Substances Data: 117378-85-5(Hazardous Substances Data)

Upstream product

• 874-60-2 4-methyl-benzoyl chloride 
• 59046-28-5 p-toluoyl-1H-1,2,3-benzotriazole 
• 99-94-5 p-Toluic acid 
• 397329-29-2 (4-methylphenyl)[1-(triisopropylsilyl)-1H-pyrrol-3-yl]methanone 
• 109-97-7 pyrrole 
• 97188-29-9 1-(phenylsulfonyl)-3-(4-methylbenzoyl)pyrrole 

Downstream Products

• 147088-90-2 2,4-bis(p-methyl)benzoylpyrrole 
• 147089-00-7 (5-Benzoyl-1H-pyrrol-3-yl)-p-tolyl-methanone 
• 156026-92-5 3-(Imidazol-1-yl-p-tolyl-methyl)-1'H-[1,3']bipyrrolyl-4'-carboxylic acid ethyl ester 
• 156026-96-9 3-(Imidazol-1-yl-p-tolyl-methyl)-1'H-[1,3']bipyrrolyl-4'-carboxylic acid 
• 156026-88-9 (E)-3-[3-(Imidazol-1-yl-p-tolyl-methyl)-pyrrol-1-yl]-acrylic acid ethyl ester 
• 156026-84-5 (E)-3-[3-(Hydroxy-p-tolyl-methyl)-pyrrol-1-yl]-acrylic acid ethyl ester 
• 117378-88-8 3-[3-(4-Methyl-benzoyl)-pyrrol-1-yl]-propionic acid ethyl ester 
• 128843-65-2 (E)-3-[3-(4-Methyl-benzoyl)-pyrrol-1-yl]-acrylic acid 
• 156026-80-1 (E)-3-[3-(4-Methyl-benzoyl)-pyrrol-1-yl]-acrylic acid ethyl ester 
• 147089-07-4 p-Tolyl-[5-(2-p-tolyl-benzo[1,3]dithiol-2-yl)-1H-pyrrol-3-yl]-methanone 
• 147089-15-4 [5-(2-Phenyl-benzo[1,3]dithiol-2-yl)-1H-pyrrol-3-yl]-p-tolyl-methanone 

Relevant articles and documents

NOVEL HETEROARYL DERIVATIVE

A compound of the following formula (1), or its prodrug or pharmaceutically acceptable salt thereof, being useful as a diabetic medicine or preventive, or blood sugar regulator, or therapeutic agent for hyperlipemia, etc. wherein the ring Z is an optionally substituted heteroaryl, W4 is a single bond, lower alkylene, etc., Ar2 is an optionally substituted aryl, etc., W3 is a single bond, lower alkylene, etc., Ar1 is an optionally substituted arylene, etc., each of W1 and W2 is an optionally substituted lower alkylene, etc., and R1 is carboxyl, an alkoxycarbonyl.

NOVEL HETEROARYL DERIVATIVE

A compound of the following formula (1), or its prodrug or pharmaceutically acceptable salt thereof, being useful as a diabetic medicine or preventive, or blood sugar regulator, or therapeutic agent for hyperlipemia, etc. (1) wherein: the ring Z is an optionally substituted heteroaryl, W4 is a single bond, lower alkylene, etc., Ar2 is an optionally substituted aryl, etc., W3 is a single bond, lower alkylene, etc., Ar1 is an optionally substituted arylene, etc., each of W1 and W2 is an optionally substituted lower alkylene, etc., and R1 is carboxyl, an alkoxycarbonyl, etc.

PYRROLE DERIVATIVE

A novel pyrrole derivative represented by the following formula (1) and a salt thereof: wherein R1 means substituted alkenyl, etc.; R2 means substituted benzoyl, etc.; and R3 to R5 each means hydrogen, alkyl, halogeno, etc. The derivative and salt have antidiabetic activity.