117428-49-6

Basic information

• Product Name: (E)-3-Methoxy-2-(2-broMoMethylphenyl)propenoic acid Methyl ester
• Synonyms: (E)-3-Methoxy-2-(2-broMoMethylphenyl)propenoic acid Methyl ester
• CAS NO: 117428-49-6
• Molecular Weight: 285.137
• Mol File: 117428-49-6.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: (E)-3-Methoxy-2-(2-broMoMethylphenyl)propenoic acid Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-Methoxy-2-(2-broMoMethylphenyl)propenoic acid Methyl ester(117428-49-6)
• EPA Substance Registry System: (E)-3-Methoxy-2-(2-broMoMethylphenyl)propenoic acid Methyl ester(117428-49-6)

Safety Data

• Hazardous Substances Data: 117428-49-6(Hazardous Substances Data)

Usage

General Description

(E)-3-Methoxy-2-(2-bromoMethylphenyl)propenoic acid Methyl ester is a chemical compound with the molecular formula C11H11BrO3. It is a methyl ester derivative of (E)-3-Methoxy-2-(2-bromoMethylphenyl)propenoic acid, which is a brominated chalcone derivative. This chemical is used in various applications, including as a starting material in organic synthesis and as a reagent in chemical reactions. It is also used in the pharmaceutical and agrochemical industries for the synthesis of various compounds. The compound is known to have potential biological activities, and its derivatives are being studied for their pharmacological properties.

Upstream product

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Relevant articles and documents

Silver-Catalyzed Olefination of Acetals and Ketals with Diazoesters to β-Alkoxyacrylates

The first silver-catalyzed reaction of acetals or ketals with diazoesters leading to trisubstituted or tetrasubstituted β-alkoxyacrylates is now reported. A broad range of acetals and ketals bearing different substituents is compatible with this protocol and thus provides an attractive approach for the synthesis of complex β-alkoxyacrylates. The power of this method was further demonstrated by the successful synthesis of picoxystrobin, which is one of the most popular agricultural fungicides commercialized by Dupont.

Synthesis and evaluation of essential oil-derived β-methoxyacrylate derivatives as high potential fungicides

Essential oils (EOs) are plant-derived aroma compounds with a wide range of biological activity, but their actions are slow, and they are typically unstable to light or heat, difficult to extract and so on. To find highly potential fungicides derived from natural EOs, a series of essential oil-based β-methoxyacrylate derivatives have been designed and synthesized. The target compounds have been screened for their potential fungicidal activity against eleven species of plant pathogen fungi, including Alternaria alternata, Phomopsis adianticola, Pestalotiopsis theae, Sclerotinia sclerotiorum, etc. Compared with intermediates I, the parent essential oils and azoxystrobin, almost all of essential oil-based β-methoxyacrylate derivatives exhibited significantly better fungicidal activity. Further investigation revealed that some compounds showed remarkable inhibitory activities against Pestalotiopsis theae, Phomopsis adianticola, Sclerotinia sclerotiorum and Magnapothe grisea at different concentrations in contrast to the commercial product azoxystrobin. Compound II-8 exhibited particularly significant fungicidal activity.

Synthesis and bioactivity of novel strobilurin derivatives containing the pyrrolidine-2,4-dione moiety

(E)-Methyl-2-(2-(bromomethyl)phenyl)-3-methoxyacrylate was reacted with substituted 1-acetylpyrrolidine-2,4-diones and 3-(1-(hydroxylamino)ethylidene) pyrrolidine-2,4-diones respectively to synthesize two series of β-methoxyacrylate derivatives containing