34241-39-9

Basic information

• Product Name: (E)-Azobis(isobutyronitrile)
• Synonyms: Azdh;Azobisisobutyronitrile;2,2'-azodiisobutyronitrile;78-67-1;Vazo;Azobisisobutylonitrile;AIBN;Genitron;Aivn
• CAS NO: 34241-39-9
• Molecular Formula: C₈H₁₂N₄
• Molecular Weight: 164.21
• Mol File: 34241-39-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 105oC
• Boiling Point: 236.2°Cat760mmHg
• Flash Point: 96.6°C
• Density: 0.95g/cm³
• CAS DataBase Reference: (E)-Azobis(isobutyronitrile)(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-Azobis(isobutyronitrile)(34241-39-9)
• EPA Substance Registry System: (E)-Azobis(isobutyronitrile)(34241-39-9)

Safety Data

• Hazardous Substances Data: 34241-39-9(Hazardous Substances Data)

Usage

Description

(E)-Azobis(isobutyronitrile), with the molecular formula C8H12N4, is a chemical compound that serves as a vital radical initiator in the polymerization process of various materials. It is known for its ability to decompose at temperatures above 64°C, releasing nitrogen gas and two isobutyronitrile radicals, which subsequently initiate the polymerization reaction. (E)-Azobis(isobutyronitrile) also finds applications in the production of organic pigments and dyes, as well as in the synthesis of certain pharmaceutical compounds. However, due to its potential fire and explosion hazard, it is crucial to handle (E)-Azobis(isobutyronitrile) with caution.

Uses

Used in Polymer Industry:
(E)-Azobis(isobutyronitrile) is used as a radical initiator for the polymerization of materials such as acrylics, methacrylics, and vinyl monomers. Its ability to decompose at elevated temperatures and generate radicals is crucial in initiating the polymerization reaction, which is essential for the production of various polymers.
Used in Pigment and Dye Production:
In the pigment and dye industry, (E)-Azobis(isobutyronitrile) is utilized in the production of organic pigments and dyes. Its chemical properties make it a valuable component in the synthesis process, contributing to the development of a wide range of colorants used in various applications.
Used in Pharmaceutical Synthesis:
(E)-Azobis(isobutyronitrile) also finds application in the synthesis of certain pharmaceutical compounds. Its role in this industry is to act as a key intermediate or reactant in the production of specific drugs, highlighting its versatility and importance in the chemical and pharmaceutical sectors.

Downstream Products

• 1155-00-6 bis(2-nitrophenyl)disulfide 
• 1666-13-3 diphenyl diselenide 
• 87705-52-0 2-methyl-2-(phenylselanyl)propanenitrile 
• 10551-67-4 dimethyl-N-(2-cyano-2-propyl)ketenimine 
• 3333-52-6 2,2,3,3-tetramethylsuccinonitrile 
• 84213-57-0 N-(1-cyano-1-methylethyl)-2-methylpropanamide 
• 78-82-0 Isobutyronitrile 
• 126-98-7 methacrylonitrile 
• 385368-79-6 2,6-bis(2,4-dimethylphenyl)-1-octyl-4-phenylphosphacyclohexane 
• 385369-07-3 2,6-bis(2,4-dimethylphenyl)-1-[2-(2-methoxy-ethoxy)ethyl]-4-phenylphosphacyclohexane 
• 385369-06-2 2,6-bis(2,4-dimethylphenyl)-1-dodecyl-4-phenylphosphacyclohexane 
• 444663-52-9 1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-methoxy-2(1H)-quinolinone 
• 180302-35-6 5-bromomethyl-2-fluorobenzonitrile 
• 83004-14-2 2-bromo-4-bromomethyl pyridine 

Relevant articles and documents

Combined use of GnRH agonist and antagonist

PCT No. PCT/JP97/01459 Sec. 371 Date Aug. 14, 1997 Sec. 102(e) Date Aug. 14, 1997 PCT Filed Apr. 25, 1997 PCT Pub. No. WO97/40846 PCT Pub. Date Nov. 6, 1997The present invention relates to a pharmaceutical luteinizing hormone releasing hormone agonist in combination with a luteinizing hormone releasing hormone antagonist. By using a luteinizing hormone releasing hormone agonist and a luteinizing hormone releasing hormone antagonist in combination, the transient exacerbation with elevation of serum testosterone and estrogen owing to the pituitary-gonadotropic action (acute action) manifested immediately following an initial dose of the luteinizing hormone releasing hormone agonist can be successfully obviated.

Efficient cis-to-trans isomerization of 1, 4-dihalobutene-2

-