1174681-32-3

Basic information

• Product Name: (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid (R)-PGME amide
• Synonyms: (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid (R)-PGME amide
• CAS NO: 1174681-32-3
• Molecular Weight: 345.352
• Mol File: 1174681-32-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid (R)-PGME amide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid (R)-PGME amide(1174681-32-3)
• EPA Substance Registry System: (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid (R)-PGME amide(1174681-32-3)

Safety Data

• Hazardous Substances Data: 1174681-32-3(Hazardous Substances Data)

Upstream product

• 115939-25-8 salvianolic acid B 
• 20283-92-5 (R)-(+)-rosmarinic acid 
• 24461-61-8 (R)-Phenylglycine methyl ester 
• 23028-17-3 danshensu 

Relevant articles and documents

Monoterpene glycosides, phenylpropanoids, and acacetin glycosides from Dracocephalum foetidum

Chemical investigation of the acetone extract from the aerial parts of the Mongolian medicinal plant Dracocephalum foetidum resulted in the isolation of three limonene glycosides, a caffeic acid trimer, four rosmarinic acid glucosides, and five acacetin acyl glycosides, together with 13 known natural products. The chemical structures of all of the compounds were determined by spectroscopic analyses. Among these compounds three showed hyaluronidase inhibitory activity. In addition, one other compound showed stronger 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity than the positive control Trolox, whereas three other compounds demonstrated a similar activity to that of Trolox.

Caffeic acid oligomers with hyaluronidase inhibitory activity from Clinopodium gracile

Eight new caffeic acid oligomers, clinopodic acids J-Q (1-8), were isolated from whole plants of Clinopodium gracile, together with nine known caffeic acid oligomers. The caffeic acid oligomers with two to four dihydrobenzofuran rings were isolated as natural products for the first time. Clinopodic acid M (4) showed the strongest hyaluronidase inhibitory activity, IC50 (19 μM) among the 22 compounds isolated from this plant.

Hyaluronidase inhibitors from Takuran, Lycopus lucidus

Takuran is a traditional herbal medicine that is produced from the herbal plant Lycopus lucidas TURCZ. (Lamiaceae). Takuran is used as a treatment for diseases in women. From Takuran, four new phenylpropanoids along with 18 known compounds were isolated, and their structures were elucidated by spectroscopic analyses. Five phenylpropanoids isolated from the plant showed hyaluronidase inhibitory activity comparable to that of rosmarinic acid.