115939-25-8

Basic information

• Product Name: Salvianolic acid B
• Synonyms: (R)-2-(((2R,3R)-4-((E)-3-((R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carbonyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid;Powdered Chinese Salvia Extract (1 g);danfensuan;[2R-[2a,3b-(R*),4[E(R*)]]]-3-Benzofurancarboxylic acid 4-[3-[1-carboxy-2-(3,4-dihydroxy-phenyl) ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydrophenyl)-2,3-dihydro-7-hydroxyl-3-[1-carboxy-2-(3,4-dihydroxyphenyl) ethyl] ester;SALVIANOLIC ACID B;Lithospermate-B;SALVIANOLIC ACID B 98.0% BY HPLC;SALVIANOLIC ACID B (RG)
• CAS NO: 115939-25-8
• Molecular Formula: C₃₆H₃₀O₁₆
• Molecular Weight: 718.61
• Product Categories: Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Miscellaneous
• Mol File: 115939-25-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 1020.3 °C at 760 mmHg
• Flash Point: 322.1 °C
• Appearance: /
• Density: 1.637 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.739
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Salvianolic acid B(CAS DataBase Reference)
• NIST Chemistry Reference: Salvianolic acid B(115939-25-8)
• EPA Substance Registry System: Salvianolic acid B(115939-25-8)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 115939-25-8(Hazardous Substances Data)

Usage

Description

Salvianolic acid B (Sal B) is a naturally occurring compound that has been isolated and purified from the crude extract of Salvia miltiorrhiza. It is a light yellow to light brown powder and is known for its high total antioxidant activities, as demonstrated by the ABTS results with an EC50 value of 1.43 ± 0.01 μg/mL.

Uses

Used in Pharmaceutical Industry:
Salvianolic acid B is used as a pharmaceutical agent for its potent antioxidant properties. The compound's ability to exhibit high total antioxidant activities makes it a promising candidate for the development of new drugs and therapies, particularly in the treatment of various diseases and conditions associated with oxidative stress.
Used in Antioxidant Applications:
Salvianolic acid B is used as an antioxidant agent for its ability to neutralize harmful free radicals and protect cells from oxidative damage. This application is particularly relevant in the context of aging, inflammation, and various chronic diseases where oxidative stress plays a significant role.
Used in Drug Delivery Systems:
Salvianolic acid B can be employed in the development of novel drug delivery systems to enhance its bioavailability and therapeutic outcomes. By incorporating Sal B into various carriers, such as organic and metallic nanoparticles, its delivery and efficacy can be improved, potentially leading to more effective treatments for a range of health conditions.

InChI:InChI=1/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28?,31-,32+/m1/s1

Upstream product

• 121570-16-9 ammonium-potassium lithospermate B 

Downstream Products

• 121570-16-9 ammonium-potassium lithospermate B 
• 127853-25-2 dipotassium salt of lithospermic acid B 
• 127854-49-3 calcium salt of lithospermic acid B 
• 121521-89-9 dimethyl heptamethyllithospermate B 
• 23028-17-3 danshensu 
• 136112-75-9 (-)-7-epi-blechnic acid 
• 1174681-30-1 (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid (S)-PGME amide 
• 1174681-32-3 (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid (R)-PGME amide 
• 142998-47-8 salvianolic acid D 
• 139-85-5 3,4-dihydroxybenzaldehyde 

Relevant articles and documents

Magnesium and ammonium-potassium lithospermates B, the active principles having a uremia-preventive effect from Salvia miltiorrhiza

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