136112-75-9

Basic information

• Product Name: Przewalskinic acid A
• Synonyms: Przewalskinic acid A;[2alpha,3beta,4(E)]-4-(2-Carboxyethenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofurancarboxylic acid
• CAS NO: 136112-75-9
• Molecular Formula: C18H14O8
• Molecular Weight: 358.3
• Mol File: 136112-75-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Przewalskinic acid A(CAS DataBase Reference)
• NIST Chemistry Reference: Przewalskinic acid A(136112-75-9)
• EPA Substance Registry System: Przewalskinic acid A(136112-75-9)

Safety Data

• Hazardous Substances Data: 136112-75-9(Hazardous Substances Data)

Usage

General Description

Przewalskinic acid A is a chemical compound classified as a sesquiterpenoid. It is known for its unique structural features such as five-, six- and seven-membered rings fused together. It was first isolated from the medicinal plants of the Salvia genus. Przewalskinic acid A is particularly notable for its potential biomedical applications. Some studies have shown that it has certain anti-tumor effects, although further research is needed to fully understand its potential in this area. It also demonstrates significant neuroprotective effects, making it a potential resource for the treatment of neurodegenerative diseases.

Upstream product

• 1609691-88-4 (2S,3R)-allyl 2-{3,4-bis(triisopropylsilyloxy)phenyl}-7-(methoxymethoxy)-2,3-dihydrobenzofuran-3-carboxylate 
• 1609691-89-5 allyl 2-[2-{3,4-bis(triisopropylsilyloxy)benzyloxy}-3-(methoxymethoxy)phenyl]-2-diazo acetate 
• 1609691-99-7 C₄₅H₆₆O₈Si₂ 
• 1609691-93-1 allyl 2-[2-{3,4-bis(triisopropylsilyloxy)benzyloxy}-3-(methoxymethoxy)phenyl]acetate 
• 1609691-92-0 2-[2-{3,4-bis(triisopropylsilyloxy)benzyloxy}-3-(methoxymethoxy)phenyl]acetic acid 
• 1609691-91-9 1-allyl-3-(methoxymethoxy)-2-[3,4-bis(triisopropylsilyloxy)benzyloxy]benzene 
• 1609691-90-8 2-allyl-6-(methoxymethoxy)phenol 
• 1609691-98-6 1-allyloxy-2-(methoxymethoxy)benzene 
• 1126-20-1 2-allyloxyphenol 
• 1609692-00-3 C₃₆H₅₄O₈Si₂ 
• 1609691-97-5 (2S,3R)-2-{3,4-bis(triisopropylsilyloxy)phenyl}-7-hydroxy-4-{(E)-3-oxo-3-(2,2,2-trichloroethoxy)prop-1-en-1-yl}-2,3-dihydrobenzofuran-3-carboxylic acid 
• 1609691-96-4 (2S,3R)-2-{3,4-bis(triisopropylsilyloxy)phenyl}-7-hydroxy-2,3-dihydrobenzofuran-3-carboxylic acid 
• 1609691-94-2 (2S,3R)-2-{3,4-bis(triisopropylsilyloxy)phenyl}-7-(methoxymethoxy)-2,3-dihydrobenzofuran-3-carboxylic acid 
• 115939-25-8 salvianolic acid B 

Relevant articles and documents

Sebestenoids A-D, BACE1 inhibitors from Cordia sebestena

Bioassay-guided fractionation of an extract prepared from the fruits of Cordia sebestena led to the isolation of sebestenoids A-D (1-4). Their structures were elucidated on the basis of extensive NMR experiments and mass spectroscopic measurements. Compounds 1-4 exhibited moderate inhibition of the aspartic protease BACE1.

Degradation kinetics and mechanism of lithospermic acid under low oxygen condition using quantitative 1H NMR with HPLC-MS

A novel quantitative 1H NMR (Q-NMR) combined with HPLC-MS method has been pro posed for investigating the degradation process of traditional Chinese medicine (TCM) components. Through this method, in-situ monitoring of dynamics degradation proc

Diastereomers of lithospermic acid and lithospermic acid B from Monarda fistulosa and Lithospermum erythrorhizon

Monardic acids A (1) and B (2), which are (7R,8R) diastereomers of lithospermic acid (LA) and lithospermic acid B, respectively, were isolated from Monarda fistulosa. A (7S,8R) isomer (3) of LA was also isolated from this plant, and a (7R,8S) isomer (7) of LA was obtained from Lithospermum erythrorhizon. The absolute configuration of 1 was confirmed by analysis of its hydrolysates, 7-epiblechnic acid and 2R-3-(3,4-dihydroxyphenyl)-2- hydroxypropanoic acid. The configuration in the dihydrobenzofuran moieties of 2, 3, and 7 was extrapolated by using the phenylglycine methyl ester method and a Cotton effect at approximately 250-260 nm in their electronic circular dichroism spectra. Diastereomers (1-3 and 7) displayed moderate hyaluronidase inhibitory and histamine release inhibitory activities.