117546-56-2

Basic information

• Product Name: 3-AzetidinaMine, 1-(1-Methylethyl)-, hydrochloride (1:2)
• Synonyms: 3-AzetidinaMine, 1-(1-Methylethyl)-, hydrochloride (1:2);1-(propan-2-yl)azetidin-3-amine dihydrochloride;1-Isopropylazetidin-3-amine dihydrochloride;1-(1-Methylethyl)-3-azetidinamine,hydrochloride(1:2);1-Isopropyl-azetidin-3-ylamine dihydrochloride;1-(PROPAN-2-YL)AZETIDIN-3-AMINE 2HCL
• CAS NO: 117546-56-2
• Molecular Formula: C6H16Cl2N2
• Molecular Weight: 187.11
• Mol File: 117546-56-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-AzetidinaMine, 1-(1-Methylethyl)-, hydrochloride (1:2)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AzetidinaMine, 1-(1-Methylethyl)-, hydrochloride (1:2)(117546-56-2)
• EPA Substance Registry System: 3-AzetidinaMine, 1-(1-Methylethyl)-, hydrochloride (1:2)(117546-56-2)

Safety Data

• Hazardous Substances Data: 117546-56-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-AzetidinaMine, 1-(1-Methylethyl)-, hydrochloride (1:2) is utilized as a key intermediate in the synthesis of a range of pharmaceutical drugs. Its unique structure and reactivity make it a valuable component in the development of new medications, contributing to the advancement of healthcare and treatment options.
Used in Chemical Industry:
In the chemical industry, 3-AzetidinaMine, 1-(1-Methylethyl)-, hydrochloride (1:2) serves as an intermediate in organic synthesis. Its properties allow it to be integrated into various chemical processes, facilitating the creation of new compounds and materials with diverse applications across different sectors.

Upstream product

• 1210273-37-2 tert-butyl 3-aminoazetidine-1-carboxylate hydrochloride 
• 193269-78-2 3-aminoazetidine-1-carboxylic acid tert-butyl ester 
• 67-64-1 acetone 

Relevant articles and documents

Optimization of a kilogram-scale synthesis of a potent cycloartenol triterpenoid-derived γ-secretase modulator

This work describes the demonstration of a kilogram-scale synthesis of a γ-secretase modulator from a plant-sterol-derived starting material. Key to developing a synthetic route capable of delivering a kilogram of the target compound was the development of a four-reaction telescope process and a selective O-alkylation of a triol intermediate. These improvements enabled the successful delivery of kilogram-scale batches of API for preclinical development studies.

COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS

The present invention provides compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method comprises administering to a patient a compound of the present invention, or composition thereof. Said method is useful for treating or lessening the severity of, for example, Alzheimer’s disease.