1175536-51-2 Usage
Description
(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide hydrosulfate is a chemical compound that belongs to the class of azole antifungals. It is specifically designed to inhibit the growth of fungi, making it a potent antifungal medication.
Used in Pharmaceutical Industry:
(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide hydrosulfate is used as an antifungal agent for treating various fungal infections. It is effective against conditions such as tinea capitis, tinea corporis, tinea cruris, tinea pedis, and onychomycosis. The hydrosulfate form of the compound enhances its solubility and other properties, allowing for efficient administration and treatment of the targeted infections.
Check Digit Verification of cas no
The CAS Registry Mumber 1175536-51-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,5,5,3 and 6 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1175536-51:
(9*1)+(8*1)+(7*7)+(6*5)+(5*5)+(4*3)+(3*6)+(2*5)+(1*1)=162
162 % 10 = 2
So 1175536-51-2 is a valid CAS Registry Number.
1175536-51-2Relevant articles and documents
The process development of ravuconazole: An efficient multikilogram scale preparation of an antifungal agent
Pesti, Jaan,Chen, Chien-Kuang,Spangler, Lori,DelMonte, Albert J.,Benoit, Serge,Berglund, Derek,Xbien, Derek,Brodfuehrer, Paul,Chan, Yeung,Corbett, Elisabeth,Costello, Carrie,DeMena, Paul,Discordia, Robert P.,Doubleday, Wendel,Gao, Zhinong,Gingras, Stephane,Grosso, John,Haas, Oscar,Kacsur, David,Lai, Chiajen,Leung, Simon,Miller, Melanie,Muslehiddinoglu, Jale,Nguyen, Nina,Qiu, Jun,Olzog, Martina,Reiff, Emily,Thoraval, Dominique,Totleben, Michael,Vanyo, Dale,Vemishetti, Purushotham,Wasylak, John,Wei, Chenkou
, p. 716 - 728 (2009)
The development of a safe, robust process for the preparation of ravuconazole (1), an antifungal agent, is described. The discovery and development of procedures enabling the efficient synthesis of multikilogram quantities of 1 and the process demonstration through plant scale preparations are presented. A controlled means to prepare a Grignard reagent and utilization of Fourier Transform Infrared spectroscopy (FTIR) monitoring to safely conduct the reaction is featured.
