117968-51-1Relevant articles and documents
Total synthesis of the proposed structure of a polyketide from Phialomyces macrosporus
Abe, Hideki,Itaya, Satoko,Sasaki, Kei,Kobayashi, Toyoharu,Ito, Hisanaka
, p. 3586 - 3589 (2015)
Total synthesis of the proposed structure of a polyketide isolated from Phialomyces macrosporus is described. The synthesis involved chemoselective epoxidation, regioselective epoxide ring opening, chemo- and diastereoselective dihydroxylation, and vinylation of lactone accompanied by the formation of a furan ring. This journal is
Synthesis of β-allylbutenolides via one-pot copper-catalyzed hydroallylation/cyclization of γ-hydroxybutynoate derivatives
Yamamoto, Yoshihiko,Shibano, Shinya,Kurohara, Takashi,Shibuya, Masatoshi
, p. 4503 - 4511 (2014/06/09)
One-pot copper-catalyzed hydroallylation/lactone cyclization of γ-hydroxybutynoate derivatives was developed to afford β-allylbutenolides.
Synthesis of 2-C-Methyl-D-erythritol 4-phosphate: The first pathway-specific intermediate in the methylerythritol phosphate route to isoprenoids
Koppisch, Andrew T.,Blagg, Brian S. J.,Poulter, C. Dale
, p. 215 - 217 (2007/10/03)
(matrix presented) 2-C-Methyl-D-erythritol 4-phosphate (4), formed from 1-deoxy-D-xylulose 5-phosphate (3), is the first pathway-specific intermediate in the methylerythritol phosphate route for the biosynthesis of isoprenoid compounds in bacteria, algae, and plant chloroplasts. In this report, 4 was synthesized from 1,2-propanediol (7) in seven steps with an overall yield of 32% and in an enantiomeric excess of 78%.
