1184722-19-7

Basic information

• Product Name: methyl (2E)-cyano[6,8-dicyano-7-(3-methoxyphenyl)-5-oxo-1,5-dihydro[1,2,4]triazolo[1,5-a]pyridin-2(3H)-ylidene]acetate
• CAS NO: 1184722-19-7
• Molecular Weight: 388.342
• Mol File: 1184722-19-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (2E)-cyano[6,8-dicyano-7-(3-methoxyphenyl)-5-oxo-1,5-dihydro[1,2,4]triazolo[1,5-a]pyridin-2(3H)-ylidene]acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2E)-cyano[6,8-dicyano-7-(3-methoxyphenyl)-5-oxo-1,5-dihydro[1,2,4]triazolo[1,5-a]pyridin-2(3H)-ylidene]acetate(1184722-19-7)
• EPA Substance Registry System: methyl (2E)-cyano[6,8-dicyano-7-(3-methoxyphenyl)-5-oxo-1,5-dihydro[1,2,4]triazolo[1,5-a]pyridin-2(3H)-ylidene]acetate(1184722-19-7)

Safety Data

• Hazardous Substances Data: 1184722-19-7(Hazardous Substances Data)

Upstream product

• 1177698-04-2 1,6-diamino-4-(3-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile 
• 3490-92-4 methyl 2-cyano-3,3-bis(methylsulfanyl)acrylate 

Relevant articles and documents

A convenient synthesis of [1,2,4]triazolo[1,5-a]pyridines and 1,8-naphthyridine of analgesic and anti-inflammatory profiles

Starting from 1,6-diamino-3,5-dicyano-4-aryl-2-pyridones, substituted triazolo[1,5-a]pyridines and 1,8-naphthyridine derivatives have been synthesized. All the synthesized compounds were fully characterized by spectroscopic, physical data, and elemental analyses. Some of triazolo[1,5-a]pyridines were tested with respect to their analgesic and anti-inflammatory activities. All tested compounds exhibited analgesic activities comparable or superior to Valdecoxib. The anti-inflammatory activity was present in all the tested compounds as well and exceeded that of Hydrocortisone.